Technology Process of 5-Benzyloxyvaleric acid methyl ester
There total 10 articles about 5-Benzyloxyvaleric acid methyl ester which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
thionyl chloride;
for 15h;
Ambient temperature;
DOI:10.1021/jo00115a013
- Guidance literature:
-
methanol; (5-benzenesulfonyl-5-nitropentyloxymethyl)benzene;
With
1,8-diazabicyclo[5.4.0]undec-7-ene;
In
dichloromethane;
at 0 ℃;
for 0.166667h;
With
ozone;
In
dichloromethane;
at -78 ℃;
for 0.166667h;
DOI:10.1016/j.tet.2019.130883
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: L-proline; ester of 3,5-di-tert-butyl-4-hydroxyphenylpropionic acid and pentaerythritol / dimethyl sulfoxide / 4 h / 40 °C / Sonication
2.1: sodium cyanoborohydride / N,N-dimethyl-formamide / 90 °C
3.1: 1,8-diazabicyclo[5.4.0]undec-7-ene / dichloromethane / 0.17 h / 0 °C
3.2: 0.17 h / -78 °C
With
ester of 3,5-di-tert-butyl-4-hydroxyphenylpropionic acid and pentaerythritol; sodium cyanoborohydride; 1,8-diazabicyclo[5.4.0]undec-7-ene; L-proline;
In
dichloromethane; dimethyl sulfoxide; N,N-dimethyl-formamide;
DOI:10.1016/j.tet.2019.130883
