(+)-Conhydrine

Base Information

Chemical Name:(+)-Conhydrine
CAS No.:495-20-5
Molecular Formula:C8H17 N O
Molecular Weight:143.229
Hs Code.:2933399090
European Community (EC) Number:207-798-1
UNII:Q21EOC14Q2
DSSTox Substance ID:DTXSID10879264
Nikkaji Number:J20.639C
Wikidata:Q409921
Wikipedia:Conhydrine
Mol file:495-20-5.mol

Synonyms:alpha-conhydrine;conhydrine

Suppliers and Price of (+)-Conhydrine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
CONHYDRINE 95.00%
5MG
$ 501.42

AK Scientific
Conhydrine
5g
$ 2088.00

Total 6 raw suppliers

Chemical Property of (+)-Conhydrine

Chemical Property:

Vapor Pressure:0.016mmHg at 25°C
Melting Point:121°
Refractive Index:1.4852 (estimate)
Boiling Point:226.7°Cat760mmHg
PKA:15.15±0.20(Predicted)
Flash Point:82.3°C
PSA：32.26000
Density:0.941g/cm³
LogP:1.22820
XLogP3:1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:143.131014166
Heavy Atom Count:10
Complexity:95.3

Purity/Quality:

99% ^*data from raw suppliers

CONHYDRINE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCC(C1CCCCN1)O
Isomeric SMILES:CC[C@H]([C@@H]1CCCCN1)O

Technology Process of (+)-Conhydrine

There total 96 articles about (+)-Conhydrine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 38726-77-1
conhydrinone hydrochloride

: 63401-12-7
C₈H₁₇NO

: 495-20-5
(+)-conhydrine

Guidance literature:: With RuCl₂[(R)-XylSDP][(S,S)-DPEN]; potassium tert-butylate; hydrogen; In isopropyl alcohol; at 20 ℃; under 38002.6 Torr; enantioselective reaction; Autoclave;
DOI:10.1021/ol901605a

Reference yield: 88.0%

: 127628-03-9
O-benzylconhydrine

: 495-20-5
(+)-conhydrine

Guidance literature:: With hydrogen; hydrogenchloride; palladium on activated charcoal; In ethanol;
DOI:10.1016/S0040-4039(01)93904-8

Reference yield: 88.0%

: 854778-92-0
(4S,5R)-5-Ethyl-4-(4-hydroxy-butyl)-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester

: 124-63-0
methanesulfonyl chloride

: 495-20-5
(+)-conhydrine

Guidance literature:: (4S,5R)-5-Ethyl-4-(4-hydroxy-butyl)-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester; methanesulfonyl chloride; With triethylamine; at -78 ℃; for 1h;

With trifluoroacetic acid; In dichloromethane;
DOI:10.1016/j.tetlet.2005.04.013