2-Methoxyisonicotinic acid

Base Information

Chemical Name:2-Methoxyisonicotinic acid
CAS No.:105596-63-2
Molecular Formula:C7H7NO3
Molecular Weight:153.137
Hs Code.:29333990
European Community (EC) Number:624-051-9
DSSTox Substance ID:DTXSID40356139
Wikidata:Q72485790
Mol file:105596-63-2.mol

Synonyms:2-methoxyisonicotinic acid;105596-63-2;2-Methoxy-4-pyridinecarboxylic acid;2-methoxypyridine-4-carboxylic acid;2-Methoxy-isonicotinic acid;4-PYRIDINECARBOXYLIC ACID, 2-METHOXY-;MFCD04115718;SCHEMBL229446;DTXSID40356139;DPNDWFVORIGXQO-UHFFFAOYSA-N;HMS1699L02;CS-D0186;BBL013255;STK503427;AKOS000206134;AC-7515;PB21858;PS-4086;2-(methyloxy)-4-pyridinecarboxylic acid;BP-11261;2-Methoxypyridine-4-carboxylic acid, 97%;AM20050634;FT-0630040;M2079;EN300-39036;A801290;W-204587;F0001-0113;Z227823722

Suppliers and Price of 2-Methoxyisonicotinic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-Methoxyisonicotinic Acid
1g
$ 75.00

TRC
2-Methoxyisonicotinic Acid
250mg
$ 55.00

TCI Chemical
2-Methoxyisonicotinic Acid >98.0%(GC)(T)
1g
$ 35.00

TCI Chemical
2-Methoxyisonicotinic Acid >98.0%(GC)(T)
5g
$ 104.00

SynQuest Laboratories
2-Methoxyisonicotinic acid
100 g
$ 344.00

SynQuest Laboratories
2-Methoxyisonicotinic acid
25 g
$ 135.00

Sigma-Aldrich
2-Methoxypyridine-4-carboxylic acid 97%
1g
$ 62.00

Matrix Scientific
2-Methoxy-4-pyridinecarboxylic acid 98%
25g
$ 74.00

Matrix Scientific
2-Methoxy-4-pyridinecarboxylic acid 98%
5g
$ 19.00

Matrix Scientific
2-Methoxy-4-pyridinecarboxylic acid 98%
100g
$ 265.00

Total 86 raw suppliers

Chemical Property of 2-Methoxyisonicotinic acid

Chemical Property:

Vapor Pressure:1.5E-06mmHg at 25°C
Melting Point:197-200 °C
Boiling Point:383 °C at 760 mmHg
PKA:4.50±0.10(Predicted)
Flash Point:185.4 °C
PSA：59.42000
Density:1.284 g/cm³
LogP:0.78840
Storage Temp.:Keep in dark place,Sealed in dry,Room Temperature
XLogP3:0.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:153.042593085
Heavy Atom Count:11
Complexity:149

Purity/Quality:

99%min ^*data from raw suppliers

2-Methoxyisonicotinic Acid ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Statements: 36/37/38-36
Safety Statements: 26-36/37/39

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=NC=CC(=C1)C(=O)O

Technology Process of 2-Methoxyisonicotinic acid

There total 10 articles about 2-Methoxyisonicotinic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 72716-86-0
4-cyano-2-methoxypyridine

: 105596-63-2
2-methoxy-isonicotinic acid

Guidance literature:: With water; sodium hydroxide; In ethanol; for 1h; Reflux;
DOI:10.1021/acs.jmedchem.6b01261

Reference yield: 78.0%

: 15855-06-8
2-chloro-6-methoxy-isonicotinic acid

: 105596-63-2
2-methoxy-isonicotinic acid

Guidance literature:: With hydrogen; triethylamine; palladium 10% on activated carbon; In methanol; at 20 ℃; under 155.149 Torr;

Reference yield:

: 5398-44-7
2,6-dichloropyridine-4-carboxylic acid

: 105596-63-2
2-methoxy-isonicotinic acid

Guidance literature:: Multi-step reaction with 3 steps

1: 120 - 130 °C

2: concentrated H₂SO₄

3: palladium; aqueous methanol. KOH / Hydrogenation

With potassium hydroxide; sulfuric acid; palladium;