N-[2-[4-(2-formamidocyclohexyl)phenyl]cyclohexyl]formamide

Base Information

• Chemical Name: N-[2-[4-(2-formamidocyclohexyl)phenyl]cyclohexyl]formamide
• CAS No.: 34668-22-9
• Molecular Formula: C₂₀H₂₈N₂O₂
• Molecular Weight: 328.455
• NSC Number: 113030
• DSSTox Substance ID: DTXSID20296988
• Mol file: 34668-22-9.mol

Synonyms:34668-22-9;NSC113030;N-[2-[4-(2-formamidocyclohexyl)phenyl]cyclohexyl]formamide;DTXSID20296988;NSC-113030

Chemical Property of N-[2-[4-(2-formamidocyclohexyl)phenyl]cyclohexyl]formamide

Chemical Property:

• XLogP3: 3.6
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 4
• Exact Mass: 328.215078140
• Heavy Atom Count: 24
• Complexity: 368

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CCC(C(C1)C2=CC=C(C=C2)C3CCCCC3NC=O)NC=O

Technology Process of N-[2-[4-(2-formamidocyclohexyl)phenyl]cyclohexyl]formamide

There total 3 articles about N-[2-[4-(2-formamidocyclohexyl)phenyl]cyclohexyl]formamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1,4-Bis-(2-nitro-4-cycloheksen-1-yl)-benzol (34668-19-4) → 1.4-Bis-(2-formamido-1-cyclohexyl)benzol (34668-22-9)

Guidance literature:

Multi-step reaction with 2 steps

1: H₂ / Raney-Ni / ethanol

2: Heating

With hydrogen; nickel; In ethanol;

Reference yield:

1,4-bis((E)-2-nitrovinyl)benzene (37630-69-6) → 1.4-Bis-(2-formamido-1-cyclohexyl)benzol (34668-22-9)

Guidance literature:

Multi-step reaction with 3 steps

1: tetrahydrofuran / 150 °C

2: H₂ / Raney-Ni / ethanol

3: Heating

With hydrogen; nickel; In tetrahydrofuran; ethanol;

Reference yield:

formic acid (64-18-6) + 1.4-Bis-(2-amino-1-cyclohexyl)benzol (34668-21-8) → 1.4-Bis-(2-formamido-1-cyclohexyl)benzol (34668-22-9)

Guidance literature:

Heating;

upstream raw materials:

formic acid

1.4-Bis-(2-amino-1-cyclohexyl)benzol

1,4-Bis-(2-nitro-4-cycloheksen-1-yl)-benzol

1,4-bis((E)-2-nitrovinyl)benzene