Chemical Property of 1,3-Difluorobenzene
Chemical Property:
- Appearance/Colour:clear colorless to yellowish liquid
- Vapor Pressure:82.7mmHg at 25°C
- Melting Point:-59 °C
- Refractive Index:1.4390
- Boiling Point:83.9 °C at 760 mmHg
- Flash Point:2.2 °C
- PSA：0.00000
- Density:1.165 g/cm3
- LogP:1.96480
- Storage Temp.:Flammables area
- Solubility.:1.1g/l
- Water Solubility.:insoluble
- XLogP3:2.4
- Hydrogen Bond Donor Count:0
- Hydrogen Bond Acceptor Count:2
- Rotatable Bond Count:0
- Exact Mass:114.02810645
- Heavy Atom Count:8
- Complexity:64.9
- Purity/Quality:
-
99% *data from raw suppliers
1,3-Difluorobenzene *data from reagent suppliers
Safty Information:
- Pictogram(s):
F, 
Xn
- Hazard Codes:F,Xn
- Statements:
11-20-2017/11/20
- Safety Statements:
7-16-29-33-7/9
- MSDS Files:
-
SDS file from LookChem
Useful:
- Canonical SMILES:C1=CC(=CC(=C1)F)F
-
Uses
1,3-Difluorobenzene has been extensively used in the synthesis of pharmaceutical and pesticide intermediate. For example, it can be used for the synthesis of fluorinated medicine such as Fluconazole, etc. and pesticide (Flucycloxuron, Diflubenzuro, etc.). It can also be used to synthesize liquid crystal materials. It is used in the laser induced fluorencence matrix study of 1,3-difluorobenzene radical cation. It is also used synthesis of 1,2,3-triazole containing fluconazole analogues.
