1,4-Difluorobenzene

Base Information Edit

Chemical Name:1,4-Difluorobenzene
CAS No.:540-36-3
Molecular Formula:C6H4F2
Molecular Weight:114.095
Hs Code.:29036990
European Community (EC) Number:208-742-9
NSC Number:10286
UNII:Y9FQ2EF0Z6
DSSTox Substance ID:DTXSID1075432
Nikkaji Number:J43.474D
Wikidata:Q27117911
Metabolomics Workbench ID:55920
ChEMBL ID:CHEMBL496192
Mol file:540-36-3.mol

Synonyms:1,4-DIFLUOROBENZENE;540-36-3;p-Difluorobenzene;Benzene, 1,4-difluoro-;para-Difluorobenzene;Benzene, p-difluoro-;2,5-difluorobenzene;1,4-Difluorbenzol;EINECS 208-742-9;NSC 10286;UNII-Y9FQ2EF0Z6;Y9FQ2EF0Z6;CHEBI:38585;NSC-10286;1,4-Difluoro-benzene;MFCD00000344;Benzene,4-difluoro-;WLN: FR DF;1,4-bis(fluoranyl)benzene;SCHEMBL13499;P-DIFLUOROBENZENE [MI];CHEMBL496192;DTXSID1075432;1,4-Difluorobenzene, >=99%;QUGUFLJIAFISSW-UHFFFAOYSA-;NSC10286;AKOS000120883;AM61574;DS-3203;1,4-Difluorobenzene, analytical standard;LS-29836;D1628;FT-0606871;EN300-20356;1,4-Difluorobenzene 2000 microg/mL in Methanol;A829919;W-105683;Q27117911;F0001-1411

Suppliers and Price of 1,4-Difluorobenzene

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
1,4-Difluorobenzene
1g
$ 50.00

TCI Chemical
1,4-Difluorobenzene >99.0%(GC)
25g
$ 24.00

TCI Chemical
1,4-Difluorobenzene >99.0%(GC)
5g
$ 14.00

SynQuest Laboratories
1,4-Difluorobenzene 98%
25 g
$ 14.00

SynQuest Laboratories
1,4-Difluorobenzene 98%
100 g
$ 38.00

Sigma-Aldrich
1,4-Difluorobenzene analytical standard
1000 mg
$ 147.00

Sigma-Aldrich
1,4-Difluorobenzene analytical standard
442249
$ 142.00

Sigma-Aldrich
1,4-Difluorobenzene ≥99%
100g
$ 69.00

Sigma-Aldrich
1,4-Difluorobenzene ≥99%
25g
$ 62.70

Sigma-Aldrich
1,4-Difluorobenzene solution certified reference material, 2000?μg/mL in methanol
1 mL
$ 31.40

Total 71 raw suppliers

Chemical Property of 1,4-Difluorobenzene Edit

Chemical Property:

Appearance/Colour:Clear colorless to light yellow liquid
Vapor Pressure:63.6mmHg at 25°C
Melting Point:-13 °C
Refractive Index:n20/D 1.441(lit.)
Boiling Point:90.4 °C at 760 mmHg
Flash Point:2.1 °C
PSA：0.00000
Density:1.165 g/cm³
LogP:1.96480
Storage Temp.:Flammables area
Solubility.:1.2g/l
XLogP3:2.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:114.02810645
Heavy Atom Count:8
Complexity:54.9

Purity/Quality:

99% ^*data from raw suppliers

1,4-Difluorobenzene ^*data from reagent suppliers

Safty Information:

Pictogram(s): F, Xn, T
Hazard Codes:F,Xn,T
Statements: 11-20-39/23/24/25-23/24/25
Safety Statements: 16-29-33-7-45-36/37-7/9

MSDS Files:: SDS file from LookChem

Useful:

Chemical Classes:Other Classes -> Halogenated Monoaromatics
Canonical SMILES:C1=CC(=CC=C1F)F
Uses 1,4-Difluorobenzene is used in method for production of prepolymers containing Polyoxymethylene block.

Technology Process of 1,4-Difluorobenzene

There total 118 articles about 1,4-Difluorobenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 455-17-4
(p-fluorophenyl)trimethylsilane

: 420-56-4
trimethylsilyl fluoride

: 540-36-3
para-difluorobenzene

Guidance literature:: With xenon fluoride; In dichloromethane; Inert atmosphere;
DOI:10.1016/j.tetlet.2009.02.090

Reference yield: 54.0%

: 1516885-12-3
C₆H₄FN₂⁽¹⁺⁾*C₆BF₈^(1-)

: 540-36-3
para-difluorobenzene

: 363-72-4
Pentafluorobenzene

: 434-90-2
decafluorobiphenyl

Guidance literature:: at 95 - 100 ℃;
DOI:10.1016/j.jfluchem.2013.08.001

Reference yield: 47.0%

: 71-43-2,26181-88-4,54682-86-9,13967-78-7,174973-66-1
benzene

: 462-06-6
fluorobenzene

: 540-36-3
para-difluorobenzene

: 367-11-3
ortho-difluorobenzene

: 74298-20-7
3,3,6-trifluoro-1,4-cyclohexadiene

: 74298-19-4
cis-3,6-difluorocyclohexadiene

: 74298-17-2
trans,cis,trans-3,4,5,6-tetrafluorocyclohexene

Guidance literature:: With silver(II) fluoride; In hexane; at 40 ℃; for 0.2h; Product distribution; Mechanism; other solvents, times, temperatures, ratios;
DOI:10.1021/jo01306a011