(3-Hydroxy-2,2-dimethoxy)propyl dihydrogen phosphate

Base Information

Chemical Name:(3-Hydroxy-2,2-dimethoxy)propyl dihydrogen phosphate
CAS No.:29909-09-9
Molecular Formula:C5H13 O7 P
Molecular Weight:216.128
Hs Code.:
European Community (EC) Number:249-947-3
DSSTox Substance ID:DTXSID30952361
Nikkaji Number:J286.987J
Wikidata:Q82930928
Mol file:29909-09-9.mol

Synonyms:29909-09-9;(3-Hydroxy-2,2-dimethoxy)propyl dihydrogen phosphate;EINECS 249-947-3;DTXSID30952361;2,2-Dimethoxy-1,3-propanediol 1-phosphoric acid;3-Hydroxy-2,2-dimethoxypropyl dihydrogen phosphate

Suppliers and Price of (3-Hydroxy-2,2-dimethoxy)propyl dihydrogen phosphate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of (3-Hydroxy-2,2-dimethoxy)propyl dihydrogen phosphate

Chemical Property:

Vapor Pressure:3.76E-08mmHg at 25°C
Boiling Point:402.4°C at 760 mmHg
Flash Point:197.2°C
PSA：115.26000
Density:1.471g/cm³
LogP:-0.92290
XLogP3:-2.6
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:6
Exact Mass:216.03988975
Heavy Atom Count:13
Complexity:183

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC(CO)(COP(=O)(O)O)OC

Technology Process of (3-Hydroxy-2,2-dimethoxy)propyl dihydrogen phosphate

There total 9 articles about (3-Hydroxy-2,2-dimethoxy)propyl dihydrogen phosphate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 819862-89-0
3-hydroxy-2,2-dimethoxypropyl dibenzyl phosphate

: 29909-09-9
phosphoric acid mono-(3-hydroxy-2,2-dimethoxy-propyl ester)

Guidance literature:: With hydrogen; palladium on activated charcoal; In methanol; at 20 ℃; for 0.75h;
DOI:10.1021/jo048697k

Reference yield:

3-hydroxy-2,2-dimethoxypropyl acetate: 36680-67-8
3-hydroxy-2,2-dimethoxypropyl acetate

: 29909-09-9
phosphoric acid mono-(3-hydroxy-2,2-dimethoxy-propyl ester)

Guidance literature:: Multi-step reaction with 3 steps

1: 93 percent / pyridine / CH₂Cl₂ / 0.5 h / -30 - 20 °C

2: 93 percent / NaOH / methanol; H₂O / 0.5 h / 20 °C

3: hydrogen / Pd/C / methanol / 0.75 h / 20 °C

With pyridine; sodium hydroxide; hydrogen; palladium on activated charcoal; In methanol; dichloromethane; water;
DOI:10.1021/jo048697k

Reference yield:

: 153214-82-5
2,2-dimethoxypropane-1,3-diol

: 29909-09-9
phosphoric acid mono-(3-hydroxy-2,2-dimethoxy-propyl ester)

Guidance literature:: Multi-step reaction with 4 steps

1: 23.88 g / lipase Amano AK (Pseudomonas fluorescens lipase) / diisopropyl ether / 18 h / 30 °C

2: 93 percent / pyridine / CH₂Cl₂ / 0.5 h / -30 - 20 °C

3: 93 percent / NaOH / methanol; H₂O / 0.5 h / 20 °C

4: hydrogen / Pd/C / methanol / 0.75 h / 20 °C

With pyridine; sodium hydroxide; lipase Amano AK (Pseudomonas fluorescens lipase); hydrogen; palladium on activated charcoal; In methanol; dichloromethane; di-isopropyl ether; water;
DOI:10.1021/jo048697k