N2,N2-Dimethylpyridine-2,5-diamine

Base Information

• Chemical Name: N2,N2-Dimethylpyridine-2,5-diamine
• CAS No.: 4928-43-2
• Molecular Formula: C7H11N3
• Molecular Weight: 137.184
• Hs Code.: 2933399090
• European Community (EC) Number: 225-564-7
• DSSTox Substance ID: DTXSID90197751
• Nikkaji Number: J203.196E
• Wikidata: Q83070526
• Mol file: 4928-43-2.mol

Synonyms:N2,N2-Dimethylpyridine-2,5-diamine;4928-43-2;N2,N2-Dimethyl-2,5-pyridinediamine;2-N,2-N-dimethylpyridine-2,5-diamine;EINECS 225-564-7;N,N-Dimethylpyridine-2,5-diamine;3-Amino-6-(dimethylamino)pyridine 3HCl;YTTRIUMCHLORIDE;N~2~,N~2~-dimethylpyridine-2,5-diamine;SCHEMBL142308;5-Amino-2-dimethylaminopyridine;2-dimethylamino-5-amino-pyridine;DTXSID90197751;2-(dimethylamino)-5-aminopyridine;N,N-Dimethyl-2,5-pyridinediamine;N,N2-dimethylpyridine-2,5-diamine;MFCD08691371;AKOS000200945;N2,N2-dimethyl-pyridine-2,5-diamine;PB31328;2-(N,N-dimethylamino)-5-aminopyridine;BS-13212;3-AMINO-6-(DIMETHYLAMINO)PYRIDINE;AM20061253;CS-0048821;FT-0681414;EN300-26542;N,N-dimethylpyridine-2,5-diamine, AldrichCPR;A871824

Chemical Property of N2,N2-Dimethylpyridine-2,5-diamine

Chemical Property:

• Vapor Pressure: 0.00317mmHg at 25°C
• Boiling Point: 283.4°C at 760 mmHg
• PKA: 7.87±0.10(Predicted)
• Flash Point: 125.2°C
• PSA: 42.15000
• Density: 1.115g/cm³
• LogP: 1.31100
• XLogP3: 0.6
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 1
• Exact Mass: 137.095297364
• Heavy Atom Count: 10
• Complexity: 103

Purity/Quality:

97% ^*data from raw suppliers

N2,N2-Dimethyl-2,5-pyridinediamine ^*data from reagent suppliers

Safty Information:

• Statements: 43
• Safety Statements: 36/37

MSDS Files:

Useful:

• Canonical SMILES: CN(C)C1=NC=C(C=C1)N

Technology Process of N2,N2-Dimethylpyridine-2,5-diamine

There total 9 articles about N2,N2-Dimethylpyridine-2,5-diamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

N,N-dimethyl-5-nitropyridin-2-amine (2554-75-8) → N2,N2-dimethylpyridine-2,5-diamine (4928-43-2)

Guidance literature:

With hydrogen; palladium 10% on activated carbon; In methanol; ethyl acetate; at 20 ℃; for 1.5h; under 2327.23 Torr;

Reference yield: 100.0%

→ N2,N2-dimethylpyridine-2,5-diamine (4928-43-2)

Guidance literature:

Reference yield: 80.0%

5-N-benzylamino-2-N,N-dimethylaminopyridine (1083329-54-7) → N2,N2-dimethylpyridine-2,5-diamine (4928-43-2)

Guidance literature:

With Pd/C; ammonium formate; In methanol;

DOI:10.1021/jo801501e

upstream raw materials:

N,N-dimethyl-5-nitropyridin-2-amine

hydrogenchloride

2-(Dimethylamino)pyridine

dimethyl amine

Downstream raw materials:

N-[6-(dimethylamino)pyridin-3-yl]-5-fluoro-1-(3-fluorobenzyl)-1H-indole-2-carboxamide

C₁₉H₂₅N₃O₂