2,3-Dimethoxy-5-((methylamino)sulphonyl)benzoic acid

Base Information

Chemical Name:2,3-Dimethoxy-5-((methylamino)sulphonyl)benzoic acid
CAS No.:74651-63-1
Molecular Formula:C₁₀H₁₃NO₆S
Molecular Weight:275.282
Hs Code.:
European Community (EC) Number:277-945-2
DSSTox Substance ID:DTXSID50996166
Nikkaji Number:J349.442J
Wikidata:Q82987837
Mol file:74651-63-1.mol

Synonyms:74651-63-1;2,3-Dimethoxy-5-((methylamino)sulphonyl)benzoic acid;EINECS 277-945-2;2,3-dimethoxy-5-[(methylamino)sulphonyl]benzoic acid;2,3-DIMETHOXY-5-[(METHYLAMINO)SULFONYL]BENZOIC ACID;2,3-dimethoxy-5-(methylsulfamoyl)benzoic acid;SCHEMBL10564370;DTXSID50996166

Suppliers and Price of 2,3-Dimethoxy-5-((methylamino)sulphonyl)benzoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of 2,3-Dimethoxy-5-((methylamino)sulphonyl)benzoic acid

Chemical Property:

Vapor Pressure:1.68E-09mmHg at 25°C
Boiling Point:466.5°C at 760 mmHg
Flash Point:235.9°C
PSA：110.31000
Density:1.372g/cm³
LogP:1.78180
XLogP3:0.4
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:5
Exact Mass:275.04635831
Heavy Atom Count:18
Complexity:390

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CNS(=O)(=O)C1=CC(=C(C(=C1)OC)OC)C(=O)O

Technology Process of 2,3-Dimethoxy-5-((methylamino)sulphonyl)benzoic acid

There total 3 articles about 2,3-Dimethoxy-5-((methylamino)sulphonyl)benzoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 5-chlorosulfonyl-2,3-dimethoxybenzoic acid

: 74-89-5
methylamine

: 74651-63-1
2,3-dimethoxy-5-(N-methylsulfamoyl)benzoic acid

Guidance literature:: With triethylamine; In dichloromethane; at 20 ℃; for 8h;
DOI:10.1016/j.bmc.2011.06.058

Reference yield: 73.0%

: 5-chlorosulfonyl-2,3-dimethoxybenzoic acid

: 593-77-1
N-Methylhydroxylamine

: 74651-63-1
2,3-dimethoxy-5-(N-methylsulfamoyl)benzoic acid

Guidance literature:: With triethylamine; In dichloromethane; at 20 ℃;

Reference yield:

: 1521-38-6
2,3-dimethoxybenzoic acid

: 74651-63-1
2,3-dimethoxy-5-(N-methylsulfamoyl)benzoic acid

Guidance literature:: Multi-step reaction with 2 steps

1: chlorosulfonic acid / 15 h / 20 °C

2: triethylamine / dichloromethane / 8 h / 20 °C

With chlorosulfonic acid; triethylamine; In dichloromethane;
DOI:10.1016/j.bmc.2011.06.058