3-Hydroxy-2,4,5-trifluorobenzoic acid

Base Information Edit

Chemical Name:3-Hydroxy-2,4,5-trifluorobenzoic acid
CAS No.:116751-24-7
Molecular Formula:C7H3F3O3
Molecular Weight:192.094
Hs Code.:29182900
European Community (EC) Number:622-500-3
DSSTox Substance ID:DTXSID90370188
Nikkaji Number:J1.635.186E
Wikidata:Q72481998
Mol file:116751-24-7.mol

Synonyms:2,4,5-Trifluoro-3-hydroxybenzoic acid;2,4,5-Trifluoro-3-hydroxybenzoicacid;

Suppliers and Price of 3-Hydroxy-2,4,5-trifluorobenzoic acid

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2,4,5-Trifluoro-3-hydroxybenzoic Acid
1g
$ 120.00

TCI Chemical
2,4,5-Trifluoro-3-hydroxybenzoic Acid >98.0%(GC)(T)
5g
$ 35.00

TCI Chemical
2,4,5-Trifluoro-3-hydroxybenzoic Acid >98.0%(GC)(T)
25g
$ 115.00

SynQuest Laboratories
2,4,5-Trifluoro-3-hydroxybenzoic acid 98%
1 kg
$ 540.00

SynQuest Laboratories
2,4,5-Trifluoro-3-hydroxybenzoic acid 98%
100 g
$ 99.00

SynQuest Laboratories
2,4,5-Trifluoro-3-hydroxybenzoic acid 98%
25 g
$ 29.00

SynQuest Laboratories
2,4,5-Trifluoro-3-hydroxybenzoic acid 98%
250 g
$ 180.00

Sigma-Aldrich
3-Hydroxy-2,4,5-trifluorobenzoic acid 97%
1g
$ 44.00

Medical Isotopes, Inc.
2,4,5-Trifluoro-3-hydroxybenzoic Acid
1 g
$ 610.00

Matrix Scientific
3-Hydroxy-2,4,5-trifluorobenzoic acid 99%
25g
$ 15.00

Total 106 raw suppliers

Chemical Property of 3-Hydroxy-2,4,5-trifluorobenzoic acid Edit

Chemical Property:

Appearance/Colour:white to light yellow-beige powder
Vapor Pressure:0.000827mmHg at 25°C
Melting Point:144-145 °C
Boiling Point:292.6 °C at 760 mmHg
PKA:2.75±0.10(Predicted)
Flash Point:130.8 °C
PSA：57.53000
Density:1.699 g/cm³
LogP:1.50770
Solubility.:soluble in Methanol
XLogP3:1.4
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:1
Exact Mass:192.00342844
Heavy Atom Count:13
Complexity:211

Purity/Quality:

99% ^*data from raw suppliers

2,4,5-Trifluoro-3-hydroxybenzoic Acid ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Statements: 36/37/38
Safety Statements: 26-36-37/39

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Canonical SMILES:C1=C(C(=C(C(=C1F)F)O)F)C(=O)O
Recent ClinicalTrials:Efficacy and Safety Assessment of Intracameral Injection of T2380 in Cataract Surgery
Recent EU Clinical Trials:Efficacy and safety assessment of intracameral T2380 (Fixed combination of lidoca?ne, phenylephrine and tropicamide) to obtain mydriasis in patients with small pupils for cataract surgery by phacoemulsification
Uses 2,4,5-Trifluoro-3-hydroxybenzoic Acid can be used to prepare quinoline derivatives as Antibacterial Agents. 3-Hydroxy-2,4,5-trifluorobenzoic acid may be used to synthesize methyl 3-methoxy-2,4,5-trifluorobenzoate and ethyl 3-ethoxy-2,4,5-trifluorobenzoate.

Technology Process of 3-Hydroxy-2,4,5-trifluorobenzoic acid

There total 12 articles about 3-Hydroxy-2,4,5-trifluorobenzoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.35%

: 652-03-9
3,4,5,6-tetrafluorophthalic acid

: 116751-24-7
2,4,5-trifluoro-3-hydroxybenzoic acid

Guidance literature:: 3,4,5,6-tetrafluorophthalic acid; With sodium hydroxide; In water; at 90 ℃; for 9h;

With hydrogenchloride; tri-n-propylamine; In water; at 140 ℃; for 7h; under 7500.75 Torr; pH=1; Temperature;