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116751-24-7

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Basic Information
CAS No.: 116751-24-7
Name: 3-Hydroxy-2,4,5-trifluorobenzoic acid
Article Data: 7
Molecular Structure:
Molecular Structure of 116751-24-7 (3-Hydroxy-2,4,5-trifluorobenzoic acid)
Formula: C7H3F3O3
Molecular Weight: 192.094
Synonyms: 2,4,5-Trifluoro-3-hydroxybenzoic acid;2,4,5-Trifluoro-3-hydroxybenzoicacid;
Density: 1.699 g/cm3
Melting Point: 144-145 °C
Boiling Point: 292.6 °C at 760 mmHg
Flash Point: 130.8 °C
Appearance: white to light yellow-beige powder
Hazard Symbols: IrritantXi
Risk Codes: 36/37/38
Safety: 26-37/39
PSA: 57.53000
LogP: 1.50770
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Synthetic route
652-03-9

3,4,5,6-tetrafluorophthalic acid

116751-24-7

2,4,5-trifluoro-3-hydroxybenzoic acid

Conditions
ConditionsYield
Stage #1: 3,4,5,6-tetrafluorophthalic acid With sodium hydroxide In water at 90℃; for 9h;
Stage #2: With hydrogenchloride; tri-n-propylamine In water at 140℃; under 7500.75 Torr; for 7h; pH=1; Temperature;		90.35%
28749-88-4

3,4,6-trifluoro-5-hydroxyphthalic acid

116751-24-7

2,4,5-trifluoro-3-hydroxybenzoic acid

Conditions
ConditionsYield
In water90%
In water90%
28889-41-0

4-methoxy-3,5,6-trifluorophthalic acid

116751-24-7

2,4,5-trifluoro-3-hydroxybenzoic acid

Conditions
ConditionsYield
In water74%
In water74%

2-bromo-3,4,6-trifluoro-5-hydroxy-benzoic acid

116751-24-7

2,4,5-trifluoro-3-hydroxybenzoic acid

Conditions
ConditionsYield
With sodium hydroxide; zinc In water at 25℃; for 2h;1.92 g

triisopropyl(2,3,6-trifluorophenoxy)silane

124-38-9

carbon dioxide

A

116751-24-7

2,4,5-trifluoro-3-hydroxybenzoic acid

B

156839-10-0

2,3,5-trifluoro-4-hydroxybenzoic acid

Conditions
ConditionsYield
Stage #1: triisopropyl(2,3,6-trifluorophenoxy)silane With 2,2,6,6-tetramethylpiperidinyl-lithium In diethyl ether
Stage #2: carbon dioxide In diethyl ether
Stage #3: With hydrogenchloride Title compound not separated from byproducts;
...Expand
124-38-9

carbon dioxide

1,2,4-trifluoro-3-(methoxymethoxy)benzene

A

116751-24-7

2,4,5-trifluoro-3-hydroxybenzoic acid

B

156839-10-0

2,3,5-trifluoro-4-hydroxybenzoic acid

Conditions
ConditionsYield
Stage #1: 1,2,4-trifluoro-3-(methoxymethoxy)benzene With n-butyllithium In tetrahydrofuran
Stage #2: carbon dioxide In tetrahydrofuran; hexane
Stage #3: With hydrogenchloride In water Title compound not separated from byproducts;
Stage #1: 1,2,4-trifluoro-3-(methoxymethoxy)benzene With lithium diisopropyl amide In tetrahydrofuran
Stage #2: carbon dioxide In tetrahydrofuran
Stage #3: With hydrogenchloride In water Title compound not separated from byproducts;
...Expand
851341-31-6

1-bromo-2,3,5-trifluoro-4-(methoxymethoxy)benzene

116751-24-7

2,4,5-trifluoro-3-hydroxybenzoic acid

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: 2,2,6,6-tetramethylpiperidine; potassium tert-butoxide; N,N,N',N'',N''-pentamethylenediamine / butyllithium / tetrahydrofuran; hexane / 0.75 h / -125 °C
1.2: tetrahydrofuran; hexane
2.1: HCl / H2O
3.1: 1.92 g / NaOH; zinc powder / H2O / 2 h / 25 °C
View Scheme

2-bromo-3,4,6-trifluoro-5-methoxymethoxy-benzoic acid

116751-24-7

2,4,5-trifluoro-3-hydroxybenzoic acid

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: HCl / H2O
2: 1.92 g / NaOH; zinc powder / H2O / 2 h / 25 °C
View Scheme
113798-74-6

2,3,6-trifluorophenol

116751-24-7

2,4,5-trifluoro-3-hydroxybenzoic acid

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: 82 percent / imidazole / dimethylformamide / 20 h / 25 °C
2.1: lithium 2,2,6,6-tetramethylpiperidide / diethyl ether
2.2: diethyl ether
2.3: hydrochloric acid
View Scheme
Multi-step reaction with 5 steps
1.1: 87 percent / N-bromosuccinimide / CHCl3 / 2 h / 0 °C
2.1: 88 percent / N-ethyldiisopropylamine / CH2Cl2 / 2 h / 25 °C
3.1: 2,2,6,6-tetramethylpiperidine; potassium tert-butoxide; N,N,N',N'',N''-pentamethylenediamine / butyllithium / tetrahydrofuran; hexane / 0.75 h / -125 °C
3.2: tetrahydrofuran; hexane
4.1: HCl / H2O
5.1: 1.92 g / NaOH; zinc powder / H2O / 2 h / 25 °C
View Scheme
Multi-step reaction with 2 steps
1.1: 87 percent / N-ethyldiisopropylamine / CH2Cl2 / 25 °C
2.1: lithium diisopropylamide / tetrahydrofuran
2.2: tetrahydrofuran
2.3: HCl / H2O
View Scheme
192446-70-1

4-bromo-2,3,6-trifluorophenol

116751-24-7

2,4,5-trifluoro-3-hydroxybenzoic acid

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: 88 percent / N-ethyldiisopropylamine / CH2Cl2 / 2 h / 25 °C
2.1: 2,2,6,6-tetramethylpiperidine; potassium tert-butoxide; N,N,N',N'',N''-pentamethylenediamine / butyllithium / tetrahydrofuran; hexane / 0.75 h / -125 °C
2.2: tetrahydrofuran; hexane
3.1: HCl / H2O
4.1: 1.92 g / NaOH; zinc powder / H2O / 2 h / 25 °C
View Scheme
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    116751-24-7

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    116751-24-7

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    116751-24-7

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    Greenutra Resource is committed to the natural ingredients, formulation and application in the field of R&D, production and sales as the “one-step” natural product solution provide

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    116751-24-7

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     China (Mainland)  |  Contact Details

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  • Casno:

    116751-24-7

    Best price 2,4,5-Trifluoro-3-Hydroxybenzoic Acid 116751-24-7

    Min.Order: 100 Kilogram

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     China (Mainland)  |  Contact Details

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  • Casno:

    116751-24-7

    3-Hydroxy-2,4,5-trifluorobenzoic acid

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     China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

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  • Casno:

    116751-24-7

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     China (Mainland)  |  Contact Details

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  • Casno:

    116751-24-7

    3-Hydroxy-2,4,5-trifluorobenzoic acid

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    Wuhan Fortuna Chemical Co., Ltd, located in the predominant Wu Han City where is a traffic hinge of China, is a big integrative chemical enterprise being engaged in producing and

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     China (Mainland)  |  Contact Details

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  • Casno:

    116751-24-7

    2,4,5-Trifluoro-3-Hydroxybenzoic Acid

    Min.Order: 0

    FOB Price:  USD $ 0.0-0.0

    Our clients, like BASF,CHEMO,Brenntag,ASR,Evonik,Merck and etc.Appearance:COA Storage:in stock Application:MSDS/TDS

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     China (Mainland)  |  Contact Details

    Business Type:Manufacturers

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    116751-24-7

    3-Hydroxy-2,4,5-trifluorobenzoic acid

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    TAIHO Unique Advantages:1.We're factory2.Free samples available3.Commodity inspection can be done4.ISO9001,Kosher certifications5.10 years experiences Storage:Store in cool &dry place Package:aluminium foil bag/fiber can/plastic drum Application:comp

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     China (Mainland)  |  Contact Details

    Business Type:Manufacturers

    Tel:+86-18120399543

    Address:No. 49 taifeng Road,Qianjiang City,Hubei,China

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  • Casno:

    116751-24-7

    3-Hydroxy-2,4,5-trifluorobenzoicacid

    Min.Order: 0

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    Ansciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali

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    China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:0086-21-50563169

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