2-(o-Methoxyphenyl)-3-methyloxazolidine

Base Information

• Chemical Name: 2-(o-Methoxyphenyl)-3-methyloxazolidine
• CAS No.: 67625-14-3
• Molecular Formula: C₁₁H₁₅NO₂
• Molecular Weight: 193.246
• DSSTox Substance ID: DTXSID20986993
• Nikkaji Number: J78.657H
• Mol file: 67625-14-3.mol

Synonyms:BRN 5526502;2-(o-Methoxyphenyl)-3-methyloxazolidine;Oxazolidine, 2-(o-methoxyphenyl)-3-methyl-;67625-14-3;2-(2-methoxyphenyl)-3-methyl-1,3-oxazolidine;DTXSID20986993;LS-100422

Chemical Property of 2-(o-Methoxyphenyl)-3-methyloxazolidine

Chemical Property:

• Vapor Pressure: 0.00736mmHg at 25°C
• Boiling Point: 269.2°C at 760 mmHg
• Flash Point: 97.5°C
• Density: 1.079g/cm³
• XLogP3: 1.5
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 2
• Exact Mass: 193.110278721
• Heavy Atom Count: 14
• Complexity: 186

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CN1CCOC1C2=CC=CC=C2OC

Technology Process of 2-(o-Methoxyphenyl)-3-methyloxazolidine

There total 1 articles about 2-(o-Methoxyphenyl)-3-methyloxazolidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(2-hydroxyethyl)(methyl)amine (109-83-1) + ortho-anisaldehyde (135-02-4) → 2-(2-Methoxy-phenyl)-3-methyl-oxazolidine (67625-14-3)

Guidance literature:

Reference yield:

2-(2-Methoxy-phenyl)-3-methyl-oxazolidine (67625-14-3) → N-(2-hydroxyethyl)-N-(2-methoxylbenzyl)methylamine (100054-98-6)

Guidance literature:

With potassium; In tetrahydrofuran; for 24h; Yield given; Ambient temperature;

DOI:10.1021/jo00076a033

Reference yield:

2-(2-Methoxy-phenyl)-3-methyl-oxazolidine (67625-14-3) + methyl iodide (74-88-4) → 2-amino>ethyl methyl ether

Guidance literature:

With 1.) K; Yield given. Multistep reaction; 1.) THF, 0 deg C 6 h, 2.) -70 deg C, 1 h;

DOI:10.1021/jo00076a033

upstream raw materials:

(2-hydroxyethyl)(methyl)amine

ortho-anisaldehyde

Downstream raw materials:

N-(2-hydroxyethyl)-N-(2-methoxylbenzyl)methylamine