4-(bromomethyl)-2,6-ditert-butyl-phenol

Base Information

• Chemical Name: 4-(bromomethyl)-2,6-ditert-butyl-phenol
• CAS No.: 2091-51-2
• Molecular Formula: C15H23 Br O
• Molecular Weight: 299.251
• Hs Code.: 2908199090
• Mol file: 2091-51-2.mol

Synonyms:p-Cresol, a-bromo-2,6-di-tert-butyl-(6CI,7CI,8CI); 2,6-Bis-(1,1-dimethylethyl)-4-bromomethylphenol; 2,6-Di-tert-butyl-4-(bromomethyl)phenol;3,5-Di-tert-butyl-4-hydroxybenzyl bromide;4-(Bromomethyl)-2,6-di-tert-butylphenol; a-Bromo-2,6-di-tert-butyl-p-cresol

Chemical Property of 4-(bromomethyl)-2,6-ditert-butyl-phenol

Chemical Property:

• Vapor Pressure: 0.000365mmHg at 25°C
• Melting Point: 54-55 °C(Solv: ligroine (8032-32-4))
• Boiling Point: 308.8°Cat760mmHg
• PKA: 10.70±0.70(Predicted)
• Flash Point: 140.6°C
• PSA: 20.23000
• Density: 1.193g/cm³
• LogP: 4.88210

Purity/Quality:

97% ^*data from raw suppliers

4-(BROMOMETHYL)-2,6-DITERT-BUTYL-PHENOL 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-(bromomethyl)-2,6-ditert-butyl-phenol

There total 8 articles about 4-(bromomethyl)-2,6-ditert-butyl-phenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

2,6-di-tert-butyl-4-methyl-phenol (128-37-0) → 4-(bromomethyl)-2,6-di-tert-butylphenol (2091-51-2)

Guidance literature:

With bromine; In tetrachloromethane; at 85 ℃; for 4 - 5h;

Reference yield: 86.0%

3,5-di-tert-butyl-4-hydroxybenzyl alcohol (88-26-6) → 4-(bromomethyl)-2,6-di-tert-butylphenol (2091-51-2)

Guidance literature:

With phosphorus tribromide; In dichloromethane;

DOI:10.1016/j.bmcl.2008.01.061

Reference yield: 43.5%

N,N-dimethyl-(3,5-di-tert-butyl-4-hydroxybenzyl)amine (88-27-7) → 4-(bromomethyl)-2,6-di-tert-butylphenol (2091-51-2) + Acetyl-(3,5-di-tert-butyl-4-hydroxy-benzyl)-dimethyl-ammonium; bromide

Guidance literature:

With Acetyl bromide; In hexane;

DOI:10.1007/BF00698436

upstream raw materials:

4-bromo-4-methyl-2,6-di-tert-butylcyclohexa-2,5-dienone

benzene

2,6-di-tert-butyl-4-methyl-phenol

Acetyl bromide

Downstream raw materials:

3',5'-di-tert-butyltyrosine ethyl ester

3',5'-di-tert-butyltyrosine benzyl ester

2,6-di-tert-butyl-4-{[4-(1,4-dimethyl-pentylamino)-phenylamino]-methyl}-phenol

diethyl 3,5-di-tert-butyl-4-hydroxybenzyl phenyl malonate