Propanamide, 3-[[3-[4-[2-(cyclopropylmethoxy)ethyl]phenoxy]-2-hydroxypropyl]amino]- N-[4-(1,4,5,6-tetrahydro-4-methyl-6-oxo-3-pyridazinyl)phenyl]-

Base Information

Chemical Name:Propanamide, 3-[[3-[4-[2-(cyclopropylmethoxy)ethyl]phenoxy]-2-hydroxypropyl]amino]- N-[4-(1,4,5,6-tetrahydro-4-methyl-6-oxo-3-pyridazinyl)phenyl]-
CAS No.:101328-82-9
Molecular Formula:C29H38N4O5
Molecular Weight:522.645
Hs Code.:
Mol file:101328-82-9.mol

Propanamide,
3-[[3-[4-[2-(cyclopropylmethoxy)ethyl]phenoxy]-2-hydroxypropyl]amino]-
N-[4-(1,4,5,6-tetrahydro-4-methyl-6-oxo-3-pyridazinyl)phenyl]-

Synonyms:

Suppliers and Price of Propanamide, 3-[[3-[4-[2-(cyclopropylmethoxy)ethyl]phenoxy]-2-hydroxypropyl]amino]- N-[4-(1,4,5,6-tetrahydro-4-methyl-6-oxo-3-pyridazinyl)phenyl]-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Propanamide, 3-[[3-[4-[2-(cyclopropylmethoxy)ethyl]phenoxy]-2-hydroxypropyl]amino]- N-[4-(1,4,5,6-tetrahydro-4-methyl-6-oxo-3-pyridazinyl)phenyl]-

Chemical Property:

Purity/Quality:: 98%min ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of Propanamide, 3-[[3-[4-[2-(cyclopropylmethoxy)ethyl]phenoxy]-2-hydroxypropyl]amino]- N-[4-(1,4,5,6-tetrahydro-4-methyl-6-oxo-3-pyridazinyl)phenyl]-

There total 8 articles about Propanamide, 3-[[3-[4-[2-(cyclopropylmethoxy)ethyl]phenoxy]-2-hydroxypropyl]amino]- N-[4-(1,4,5,6-tetrahydro-4-methyl-6-oxo-3-pyridazinyl)phenyl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 111794-56-0
6-<4-<3-phenoxy>-2-hydroxypropyl>amino>propionamido>phenyl>-5-methyl-4,5-dihydro-3(2H)-pyridazinone

: 101328-82-9
6-[4-[3-[2-hydroxy-3-[4-(2-(cyclopropylmethoxy) ethyl)phenoxy]propylamino]propionamido]phenyl]-5-methyl-4,5-dihydro-3 (2H)-pyridazinone

Guidance literature:: With hydrogen; palladium dihydroxide; In ethanol; for 6h; under 1290.1 Torr;
DOI:10.1021/jm00397a013

Reference yield:

: 63659-16-5
4-[2-(cyclopropylmethoxy)-ethyl]-phenol

: 101328-82-9
6-[4-[3-[2-hydroxy-3-[4-(2-(cyclopropylmethoxy) ethyl)phenoxy]propylamino]propionamido]phenyl]-5-methyl-4,5-dihydro-3 (2H)-pyridazinone

Guidance literature:: Multi-step reaction with 3 steps

1: base

2: 38 percent / propan-1-ol / 22 h / Heating

3: H₂ / palladium hydroxide on carbon / ethanol / 6 h / 1290.1 Torr

With hydrogen; palladium dihydroxide; In propan-1-ol; ethanol;
DOI:10.1021/jm00397a013

Reference yield:

: 63659-17-6
1-[2-(cyclopropyl-methoxy)-ethyl]-4-(2,3-epoxypropoxy)-benzene

: 101328-82-9
6-[4-[3-[2-hydroxy-3-[4-(2-(cyclopropylmethoxy) ethyl)phenoxy]propylamino]propionamido]phenyl]-5-methyl-4,5-dihydro-3 (2H)-pyridazinone

Guidance literature:: Multi-step reaction with 2 steps

1: 38 percent / propan-1-ol / 22 h / Heating

2: H₂ / palladium hydroxide on carbon / ethanol / 6 h / 1290.1 Torr

With hydrogen; palladium dihydroxide; In propan-1-ol; ethanol;
DOI:10.1021/jm00397a013