2h-Indazol-3-amine,2-phenyl-

Base Information

• Chemical Name: 2h-Indazol-3-amine,2-phenyl-
• CAS No.: 1019-13-2
• Molecular Formula: C13H11N3
• Molecular Weight: 209.25
• DSSTox Substance ID: DTXSID101310003
• Nikkaji Number: J2.374.129F
• Mol file: 1019-13-2.mol

Synonyms:2h-indazol-3-amine,2-phenyl-;1019-13-2;2-phenyl-2H-indazol-3-amine;2H-Indazol-3-amine, 2-phenyl-;SCHEMBL1092954;2-PHENYLINDAZOL-3-AMINE;WVHNUFAIFHNMRL-UHFFFAOYSA-N;DTXSID101310003

Chemical Property of 2h-Indazol-3-amine,2-phenyl-

Chemical Property:

• XLogP3: 2.9
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 209.095297364
• Heavy Atom Count: 16
• Complexity: 237

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)N2C(=C3C=CC=CC3=N2)N

Technology Process of 2h-Indazol-3-amine,2-phenyl-

There total 12 articles about 2h-Indazol-3-amine,2-phenyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

(E)-2-(phenyldiazenyl)benzonitrile (38302-59-9) → 3-amino-2-phenyl-2H-indazole (1019-13-2)

Guidance literature:

With tin(ll) chloride; In ethanol; Heating;

DOI:10.1021/jo060965m

Reference yield: 91.0%

2-Chlorobenzonitrile (873-32-5) + phenylhydrazine (100-63-0) → 3-amino-2-phenyl-2H-indazole (1019-13-2)

Guidance literature:

With caesium carbonate; palladium dichloride; tri tert-butylphosphoniumtetrafluoroborate; In 1,4-dioxane; at 100 - 110 ℃; Solvent; regioselective reaction; Inert atmosphere;

DOI:10.1021/acs.orglett.0c02766

Reference yield: 86.0%

o-cyanobromobenzene (2042-37-7) + phenylhydrazine (100-63-0) → 3-amino-2-phenyl-2H-indazole (1019-13-2)

Guidance literature:

With caesium carbonate; palladium dichloride; tri tert-butylphosphoniumtetrafluoroborate; In 1,4-dioxane; at 100 - 110 ℃; Solvent; regioselective reaction; Inert atmosphere;

DOI:10.1021/acs.orglett.0c02766

upstream raw materials:

2-(phenylazo-1-yl)benzonitrile

2,3-Dimethyl-2-butene

(E)-2-(phenyldiazenyl)benzonitrile

(E)-1-(2-iodophenyl)-2-phenyldiazene

Downstream raw materials:

3-(Methylamino)-2-phenyl-1H-indazolium-4-methylbenzolsulfonat

(E)-2-(phenyldiazenyl)benzonitrile

(2-phenyl-2H-indazol-3-yl)-[1-phenyl-methylidene]-amine

cyclohexyl-(2-phenyl-2H-indazol-3-yl)-amine