4-METHOXYNAPHTHALEN-1-YLMETHYLAMINE

Base Information

• Chemical Name: 4-METHOXYNAPHTHALEN-1-YLMETHYLAMINE
• CAS No.: 101931-31-1
• Molecular Formula: C12H13NO
• Molecular Weight: 187.241
• Mol file: 101931-31-1.mol

Synonyms:4-methoxy-1-naphthylmethylamine;4-methoxy-1-naphthalenemethylamine;4-Methoxy-1-aminomethyl-naphthalin;1-naphthalenemethanamine,4-methoxy;

Chemical Property of 4-METHOXYNAPHTHALEN-1-YLMETHYLAMINE

Chemical Property:

• Boiling Point: 344.3±17.0 °C(Predicted)
• PKA: 9.44±0.30(Predicted)
• PSA: 35.25000
• Density: 1.117±0.06 g/cm3(Predicted)
• LogP: 3.00740

Purity/Quality:

85.0-99.8% ^*data from raw suppliers

1-Naphthalenemethanamine 4-methoxy-95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-METHOXYNAPHTHALEN-1-YLMETHYLAMINE

There total 5 articles about 4-METHOXYNAPHTHALEN-1-YLMETHYLAMINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-methoxy-1-naphthalenecarbonitrile (5961-55-7) → 1-(aminomethyl)-4-methoxynaphthalene (101931-31-1)

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran; at 0 ℃; for 1h;

DOI:10.1021/jm000472o

Reference yield:

4-methoxy-1-naphthaldehyde (15971-29-6) → 1-(aminomethyl)-4-methoxynaphthalene (101931-31-1)

Guidance literature:

4-methoxy-1-naphthaldehyde; With Rink resin; trimethyl orthoformate; at 25 ℃; for 2h;

With lithium borohydride; In tetrahydrofuran; at 65 ℃; for 5h;

With trifluoroacetic acid; In dichloromethane; at 25 ℃;

DOI:10.1021/jm051076e

Reference yield:

→ 1-(aminomethyl)-4-methoxynaphthalene (101931-31-1)

Guidance literature:

With sodium amalgam; ethanol; acetic acid; at 50 - 70 ℃;

DOI:10.1002/ardp.19392770805

upstream raw materials:

ethanol

α-4-methoxy-naphthaldoxime-(1)

4-methoxy-1-naphthalenecarbonitrile

4-methoxy-1-naphthaldehyde

Downstream raw materials:

4-Chloro-5-(4-methoxy-1-naphthylmethylamino)-3(2H)pyridazinone