2-Anilino-4H-3,1-benzoxazin-4-one

Base Information

• Chemical Name: 2-Anilino-4H-3,1-benzoxazin-4-one
• CAS No.: 1026-16-0
• Molecular Formula: C14H10N2O2
• Molecular Weight: 238.246
• Hs Code.: 2934999090
• Mol file: 1026-16-0.mol

Synonyms:2-(phenylamino)-4H-benzo[d][1,3]oxazin-4-one;2-anilino-benzo[d][1,3]oxazin-4-one;2-anilino-benz[d][1,3]oxazin-4-one;2-phenylamino-4H-3,1-benzoxazin-4-one;2-Anilino-4H-3,1-benzoxazin-4-one;2-Anilino-benz[d][1,3]oxazin-4-on;

Chemical Property of 2-Anilino-4H-3,1-benzoxazin-4-one

Chemical Property:

• PSA: 58.36000
• LogP: 2.35350

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-Anilino-4H-3,1-benzoxazin-4-one

There total 16 articles about 2-Anilino-4H-3,1-benzoxazin-4-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

methyl 2-(3-phenylureido)benzoate (2321-50-8) → 2-(phenylamino)-4H-benzo[d][1,3]oxazin-4-one (1026-16-0)

Guidance literature:

With sulfuric acid; for 1h;

Reference yield: 96.0%

carbon monoxide (201230-82-2) + 1-azido-2-iodo-benzene (54467-95-7) + aniline (62-53-3) → 2-(phenylamino)-4H-benzo[d][1,3]oxazin-4-one (1026-16-0)

Guidance literature:

With palladium on activated charcoal; triethylamine; XPhos; In tetrahydrofuran; at 80 ℃; for 14h; under 3750.38 Torr; Reagent/catalyst; Solvent; Catalytic behavior; Autoclave; Inert atmosphere;

DOI:10.1021/acs.orglett.9b00966

Reference yield: 94.0%

N-phenyl-N'-(2-carboxyphenyl)-urea (2164-95-6) → 2-(phenylamino)-4H-benzo[d][1,3]oxazin-4-one (1026-16-0)

Guidance literature:

With 1,3,5-trichloro-2,4,6-triazine; sodium carbonate; triphenylphosphine; In tetrahydrofuran; for 0.0166667h; chemoselective reaction;

DOI:10.1055/s-0036-1588125

upstream raw materials:

methyl N-phenyldithiocarbamate

potassium anthranilate

2,1-benzisothiazolin-3(1H)-one

phenyl isocyanate

Downstream raw materials:

3-amino-2,4(1H,3H)-quinazolinedione

3-phenyl-2,4-(1H,3H)-quinazolinedione

1-(2-Hydrazinocarbonyl-phenyl)-3-phenyl-urea

2-anilinoquinazolin-4(3H)-one