Cyclopentanone, 3-cyclohexyl-

Base Information

• Chemical Name: Cyclopentanone, 3-cyclohexyl-
• CAS No.: 10264-57-0
• Molecular Formula: C11H18O
• Molecular Weight: 166.263
• DSSTox Substance ID: DTXSID40455338
• Nikkaji Number: J741.129D
• Mol file: 10264-57-0.mol

Synonyms:3-Cyclohexylcyclopentanone;3-cyclohexyl-cyclopentanone;Cyclopentanone, 3-cyclohexyl-;10264-57-0;SCHEMBL3975742;DTXSID40455338;ZKWXHMQLBLFZHP-UHFFFAOYSA-N;AKOS013846395

Chemical Property of Cyclopentanone, 3-cyclohexyl-

Chemical Property:

• XLogP3: 3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 1
• Exact Mass: 166.135765193
• Heavy Atom Count: 12
• Complexity: 168

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CCC(CC1)C2CCC(=O)C2

Technology Process of Cyclopentanone, 3-cyclohexyl-

There total 34 articles about Cyclopentanone, 3-cyclohexyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

3-cyclohexylcyclopent-2-en-1-one (126457-89-4) → (R)-3-cyclohexylcyclopentanone (10264-57-0,145100-67-0,145100-68-1)

Guidance literature:

With di-tert-butyl 1,4-dihydro-2,6-dimethyl-3,5-pyridine-dicarboxylate; (2S,5S)-5-benzyl-3-methyl-2-(5-methyl-furan-2-yl)-imidazolidin-4-one; trichloroacetic acid; In diethyl ether; at 0 - 20 ℃; for 23h;

Reference yield: 89.0%

crotonic acid methyl ester (623-43-8) + Cyclohexyl iodide (626-62-0) → 3-cyclohexyl-1-cyclopentanone (10264-57-0)

Guidance literature:

With indium; N-ethylpiperidine hypophosphite; cetyltrimethylammonim bromide; 4,4'-dicyano-4,4'-azo-di-valeric acid; In 1,4-dioxane; water; at 80 ℃; for 2h;

Reference yield: 82.0%

cyclopent-2-enone (930-30-3) + dicyclohexylzinc(II) (15658-08-9) → 3-cyclohexyl-1-cyclopentanone (10264-57-0)

Guidance literature:

With 1-methyl-pyrrolidin-2-one; chloro-trimethyl-silane; In tetrahydrofuran; at -30 ℃;

DOI:10.1016/0040-4039(96)00915-X

upstream raw materials:

cyclopent-2-enone

cyclohexane

cyclohexylmagnesium bromide

1-bromocyclohexane