2-Hydroxy-N-(4-methoxyphenyl)propanamide

Base Information

Chemical Name:2-Hydroxy-N-(4-methoxyphenyl)propanamide
CAS No.:103095-64-3
Molecular Formula:C10H13NO3
Molecular Weight:195.218
Hs Code.:
DSSTox Substance ID:DTXSID50508829
Mol file:103095-64-3.mol

Synonyms:2-Hydroxy-N-(4-methoxyphenyl)propanamide;103095-64-3;DTXSID50508829

Suppliers and Price of 2-Hydroxy-N-(4-methoxyphenyl)propanamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of 2-Hydroxy-N-(4-methoxyphenyl)propanamide

Chemical Property:

XLogP3:0.8
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:195.08954328
Heavy Atom Count:14
Complexity:188

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C(=O)NC1=CC=C(C=C1)OC)O

Technology Process of 2-Hydroxy-N-(4-methoxyphenyl)propanamide

There total 4 articles about 2-Hydroxy-N-(4-methoxyphenyl)propanamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 849585-22-4,106989-11-1,26811-96-1,31587-11-8,26100-51-6
LACTIC ACID

: 104-94-9
4-methoxy-aniline

: 103095-64-3
N-(4-methoxyphenyl)-2-hydroxypropanamide

Guidance literature:: In neat (no solvent); at 70 ℃; for 8h; Green chemistry;
DOI:10.3184/174751915X14295180195555

Reference yield: 80.0%

: pentacarbonyl((trimethylsilylmethyl)((tetramethylammonio)oxy)carbene)chromium⁽⁰⁾

: 104-94-9
4-methoxy-aniline

: (CH₃)3SiCH₂CH(OH)C(O)NHC₆H₄OCH₃

: 103095-64-3
N-(4-methoxyphenyl)-2-hydroxypropanamide

Guidance literature:: With chloro-trimethyl-silane; air; In diethyl ether; Irradiation (UV/VIS); to a suspn. of Cr-compd. TMSCl is added (0°C), mixt. is stirred for 1 h, a soln. of p-anisidine is added, mixt. is irradiated (24 h, room temp., Ar), solvent is removed in vac., residue is dissolved in EtOAc, filtered and oxidized (air; sunlight); mixt. is filtered (Celite), solvent is removed, residue is washed with aq. HCl and chromd. (hexane/EtOAc), elem. anal.;
DOI:10.1016/0020-1693(94)03917-8

Reference yield: 50.0%

: 15975-93-6
pentacarbonyl((methyl)((tetramethylammonio)oxy)carbene)chromium⁽⁰⁾

: 104-94-9
4-methoxy-aniline

: 103095-64-3
N-(4-methoxyphenyl)-2-hydroxypropanamide

Guidance literature:: With chloro-trimethyl-silane; air; In diethyl ether; Irradiation (UV/VIS); to a suspn. of Cr-compd. TMSCl is added (0°C), mixt. is stirred (1 h), a soln. of p-anisidine is added, mixt. is irradiated for 24 h (room temp., Ar), solvent is removed (vac.), residue is dissolved in EtOAc, filtered and oxidized (air; sunlight); mixt. is filtered (Celite), solvent is removed, residue is washed with aq. HCl and chromd., elem. anal.;
DOI:10.1016/0020-1693(94)03917-8