6-(dimethylamino)-9-(4-methylbenzyl)-2-(trifluoromethyl)-9H-purine

Base Information

Chemical Name:6-(dimethylamino)-9-(4-methylbenzyl)-2-(trifluoromethyl)-9H-purine
CAS No.:117860-34-1
Molecular Formula:C16H16 F3 N5
Molecular Weight:335.33
Hs Code.:
Mol file:117860-34-1.mol

Synonyms:6-(dimethylamino)-9-(4-methylbenzyl)-2-(trifluoromethyl)-9H-purine

Suppliers and Price of 6-(dimethylamino)-9-(4-methylbenzyl)-2-(trifluoromethyl)-9H-purine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
6-(DIMETHYLAMINO)-9-(4-METHYLBENZYL)-2-(TRIFLUOROMETHYL)-9H-PURINE 95.00%
5MG
$ 505.64

Total 1 raw suppliers

Chemical Property of 6-(dimethylamino)-9-(4-methylbenzyl)-2-(trifluoromethyl)-9H-purine

Chemical Property:

Vapor Pressure:7.14E-06mmHg at 25°C
Boiling Point:376.7°Cat760mmHg
Flash Point:181.6°C
PSA：46.84000
Density:1.33g/cm³
LogP:3.26780

Purity/Quality:: 6-(DIMETHYLAMINO)-9-(4-METHYLBENZYL)-2-(TRIFLUOROMETHYL)-9H-PURINE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 6-(dimethylamino)-9-(4-methylbenzyl)-2-(trifluoromethyl)-9H-purine

There total 8 articles about 6-(dimethylamino)-9-(4-methylbenzyl)-2-(trifluoromethyl)-9H-purine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

: 122488-53-3
6-(dimethylamino)-2-(trifluoromethyl)-9H-purine

: 104-81-4
4-Methylbenzyl bromide

: 117860-34-1
Dimethyl-[9-(4-methyl-benzyl)-2-trifluoromethyl-9H-purin-6-yl]-amine

Guidance literature:: With potassium carbonate; In N,N-dimethyl-formamide; for 48h; Ambient temperature;
DOI:10.1021/jm00128a016

Reference yield: 35.0%

: 105183-02-6
6-chloro-9-(4-methylbenzyl)-2-(trifluoromethyl)-9H-purine

: 124-40-3
dimethyl amine

: 117860-34-1
Dimethyl-[9-(4-methyl-benzyl)-2-trifluoromethyl-9H-purin-6-yl]-amine

Guidance literature:: In ethanol; for 16h; Ambient temperature;
DOI:10.1021/jm00121a039

Reference yield:

: 104-81-4
4-Methylbenzyl bromide

: 117860-34-1
Dimethyl-[9-(4-methyl-benzyl)-2-trifluoromethyl-9H-purin-6-yl]-amine

Guidance literature:: Multi-step reaction with 5 steps

1: 1) NaH / 1) DMF, 6 h, 2) ambient temp., 16 h

2: 42 percent / trifluoroacetic acid / 16 h / Heating

3: 24 percent / NaOMe / dimethylformamide / 24 h / Heating

4: 54 percent / SOCl₂ / CHCl₃; dimethylformamide / 4 h / Heating

5: 35 percent / ethanol / 16 h / Ambient temperature

With thionyl chloride; sodium methylate; sodium hydride; In ethanol; chloroform; N,N-dimethyl-formamide; trifluoroacetic acid;
DOI:10.1021/jm00121a039