4-(3-Methoxyphenyl)-1,2-dihydronaphthalene

Base Information

• Chemical Name: 4-(3-Methoxyphenyl)-1,2-dihydronaphthalene
• CAS No.: 107328-74-5
• Molecular Formula: C17H16O
• Molecular Weight: 236.313
• DSSTox Substance ID: DTXSID10567790
• Nikkaji Number: J2.752.002B
• Wikidata: Q82453804
• Mol file: 107328-74-5.mol

Synonyms:107328-74-5;4-(3-Methoxyphenyl)-1,2-dihydronaphthalene;1-(3-Methoxyphenyl)-3,4-dihydronaphthalene;SCHEMBL8268146;DTXSID10567790;FYJUUZAHTXLVRO-UHFFFAOYSA-N

Chemical Property of 4-(3-Methoxyphenyl)-1,2-dihydronaphthalene

Chemical Property:

• XLogP3: 4.2
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 236.120115130
• Heavy Atom Count: 18
• Complexity: 307

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=CC=CC(=C1)C2=CCCC3=CC=CC=C32

Technology Process of 4-(3-Methoxyphenyl)-1,2-dihydronaphthalene

There total 4 articles about 4-(3-Methoxyphenyl)-1,2-dihydronaphthalene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

tris-(3-methoxy-phenyl)-bismuthane (95149-16-9) + 1,2-dihydro-4-iodonaphthalene (149512-01-6) → 1-(3-methoxyphenyl)-3,4-dihydronaphthalene (107328-74-5)

Guidance literature:

With bis-triphenylphosphine-palladium(II) chloride; caesium carbonate; In N,N-dimethyl acetamide; at 60 ℃; for 1h; Inert atmosphere;

DOI:10.1002/ejoc.200900487

Reference yield:

3-methoxyphenyl bromide (2398-37-0) + 3,4-dihydronaphthalene-1(2H)-one (529-34-0) → 1-(3-methoxyphenyl)-3,4-dihydronaphthalene (107328-74-5)

Guidance literature:

With hydrogenchloride; toluene-4-sulfonic acid; magnesium; In toluene;

Reference yield:

3-methoxyphenyl bromide (2398-37-0) + ammonium chloride + 3,4-dihydronaphthalene-1(2H)-one (529-34-0) → 1-(3-methoxyphenyl)-3,4-dihydronaphthalene (107328-74-5)

Guidance literature:

With sodium hydrogencarbonate; toluene-4-sulfonic acid; In tetrahydrofuran; water; toluene;

upstream raw materials:

(3-methoxyphenyl)magnesium bromide

3,4-dihydronaphthalene-1(2H)-one

3-methoxyphenyl bromide

tris-(3-methoxy-phenyl)-bismuthane

Downstream raw materials:

3-(2-nitro-3,4-dihydro-[1]naphthyl)-anisole

1-(3-Methoxyphenyl)-2-oxo-1,2,3,4-tetrahydronaphthalene