3-BENZYLOXAZOLIDINE

Base Information

• Chemical Name: 3-BENZYLOXAZOLIDINE
• CAS No.: 13657-16-4
• Molecular Formula: C10H13 N O
• Molecular Weight: 163.219
• Hs Code.: 2934999090
• Mol file: 13657-16-4.mol

Synonyms:Oxazolidine,3-benzyl- (6CI,8CI); 3-Benzyl-1,3-oxazolidine; 3-Benzyloxazolidine; NSC 261661

Chemical Property of 3-BENZYLOXAZOLIDINE

Chemical Property:

• Refractive Index: 1.5330-1.5350
• Boiling Point: 236.1°Cat760mmHg
• PKA: 6.50±0.20(Predicted)
• Flash Point: 68.5°C
• PSA: 12.47000
• Density: 1.094g/cm³
• LogP: 1.41420

Purity/Quality:

97% ^*data from raw suppliers

3-Benzyloxazolidine ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn
• Hazard Codes: Xn
• Statements: 36/37/38-22
• Safety Statements: 26-36/37/39

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-BENZYLOXAZOLIDINE

There total 7 articles about 3-BENZYLOXAZOLIDINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

formaldehyd (50-00-0,30525-89-4,61233-19-0) + N-Benzylethanolamine (104-63-2) → 3-benzyl-1,3-oxazolidine (13657-16-4)

Guidance literature:

In benzene; for 20h; Heating;

DOI:10.1016/S0040-4020(97)00922-8

Reference yield: 90.0%

formaldehyd (50-00-0,30525-89-4,61233-19-0) + N-benzylglycine (17136-36-6) → 3-benzyl-1,3-oxazolidine (13657-16-4)

Guidance literature:

In toluene; Heating;

Reference yield: 75.0%

formaldehyd (50-00-0,30525-89-4,61233-19-0) + ethanolamine (141-43-5) + phenylboronic acid (98-80-6) → 3-benzyl-1,3-oxazolidine (13657-16-4)

Guidance literature:

In water; toluene; at 80 ℃; for 1.5h; Sealed tube;

DOI:10.1007/s10593-019-02511-8

upstream raw materials:

formaldehyd

N-benzylglycine

N-benzyl-N-(methoxymethyl)-N-[(trimethylsilyl)methyl]amine

N-Benzylethanolamine

Downstream raw materials:

4-benzyl-8a-methyl-(5ar,8ac)-octahydro-furo[3,2-f][1,4]oxazepine

4-benzyl-8a-methyl-(5ar,8at)-octahydro-furo[3,2-f][1,4]oxazepine

4-benzyl-(5ar,9at)-octahydro-pyrano[3,2-f][1,4]oxazepine

4-benzyl-(5ar,9ac)-octahydro-pyrano[3,2-f][1,4]oxazepine