1,4-Diacetyl-2-methylimidazole

Base Information

Chemical Name:1,4-Diacetyl-2-methylimidazole
CAS No.:108512-13-6
Molecular Formula:C8H10N2O2
Molecular Weight:166.17700
Hs Code.:2933290090
DSSTox Substance ID:DTXSID80549982
Wikidata:Q82429186
Mol file:108512-13-6.mol

Synonyms:1,4-DIACETYL-2-METHYLIMIDAZOLE;108512-13-6;1-(1-ACETYL-2-METHYLIMIDAZOL-4-YL)ETHANONE;DTXSID80549982;AKOS006329624;1,1'-(2-Methyl-1H-imidazole-1,4-diyl)di(ethan-1-one)

Suppliers and Price of 1,4-Diacetyl-2-methylimidazole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
1,4-DIACETYL-2-METHYLIMIDAZOLE 95.00%
5MG
$ 504.06

Total 2 raw suppliers

Chemical Property of 1,4-Diacetyl-2-methylimidazole

Chemical Property:

Vapor Pressure:0.000235mmHg at 25°C
Boiling Point:325.1oC at 760 mmHg
Flash Point:150.4oC
PSA：51.96000
Density:1.18g/cm3
LogP:1.05420
XLogP3:0.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:166.074227566
Heavy Atom Count:12
Complexity:215

Purity/Quality:

95% ^*data from raw suppliers

1,4-DIACETYL-2-METHYLIMIDAZOLE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=NC(=CN1C(=O)C)C(=O)C

Technology Process of 1,4-Diacetyl-2-methylimidazole

There total 3 articles about 1,4-Diacetyl-2-methylimidazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

: 78210-66-9
4⁽⁵⁾-acetyl-2-methyl-1H-imidazole

: 75-36-5
acetyl chloride

: 108512-13-6
1,4-diacetyl-2-methylimidazole

Guidance literature:: With TEA; In chloroform; for 4.5h;
DOI:10.1021/jo00389a015

Reference yield:

: 100499-63-6
N-(5-methyl-4-isoxazolyl)acetamide

: 108512-13-6
1,4-diacetyl-2-methylimidazole

Guidance literature:: Multi-step reaction with 3 steps

1: 98 percent / H₂ / 10percent Pd on C / methanol / 1 h / 2327.2 Torr / Ambient temperature

2: NaOH / ethanol / 1 h / Heating

3: 71 percent / TEA / CHCl₃ / 4.5 h

With sodium hydroxide; TEA; hydrogen; palladium on activated charcoal; In methanol; ethanol; chloroform;
DOI:10.1021/jo00389a015

Reference yield:

: 100499-65-8
3-acetamido-4-amino-3-buten-2-one

: 108512-13-6
1,4-diacetyl-2-methylimidazole

Guidance literature:: Multi-step reaction with 2 steps

1: NaOH / ethanol / 1 h / Heating

2: 71 percent / TEA / CHCl₃ / 4.5 h

With sodium hydroxide; TEA; In ethanol; chloroform;
DOI:10.1021/jo00389a015