2-Methyl-1-phenylquinazolin-4(1H)-one

Base Information

Chemical Name:2-Methyl-1-phenylquinazolin-4(1H)-one
CAS No.:1086-20-0
Molecular Formula:C15H12N2O
Molecular Weight:236.273
Hs Code.:
ChEMBL ID:CHEMBL154350
DSSTox Substance ID:DTXSID20508770
Wikidata:Q82365927
Mol file:1086-20-0.mol

Synonyms:2-Methyl-1-phenylquinazolin-4(1H)-one;1086-20-0;2-methyl-1-phenyl-1,4-dihydroquinazolin-4-one;4(1h)-quinazolinone,2-methyl-1-phenyl-;CHEMBL154350;SCHEMBL11447666;DTXSID20508770

Suppliers and Price of 2-Methyl-1-phenylquinazolin-4(1H)-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of 2-Methyl-1-phenylquinazolin-4(1H)-one

Chemical Property:

XLogP3:2.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:1
Exact Mass:236.094963011
Heavy Atom Count:18
Complexity:358

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=NC(=O)C2=CC=CC=C2N1C3=CC=CC=C3

Technology Process of 2-Methyl-1-phenylquinazolin-4(1H)-one

There total 4 articles about 2-Methyl-1-phenylquinazolin-4(1H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.1%

: 75-36-5
acetyl chloride

: 1211-19-4
2-phenylaminobenzamide

: 1086-20-0
2-methyl-1-phenyl-4(1H)-quinazolinone

Guidance literature:: In acetic acid; for 3h; Ambient temperature;
DOI:10.1248/cpb.28.702

Reference yield:

: 28144-70-9,88-68-6
anthranilic acid amide

: 1086-20-0
2-methyl-1-phenyl-4(1H)-quinazolinone

Guidance literature:: Multi-step reaction with 2 steps

1: copper(l) chloride; triethylamine / methanol / 12 h / 20 °C

2: acetic acid / 3 h / 20 °C

With acetic acid; triethylamine; copper(l) chloride; In methanol; 1: |Chan-Lam Coupling;
DOI:10.1039/c7ob02491f

Reference yield:

: 98-80-6
phenylboronic acid

: 1086-20-0
2-methyl-1-phenyl-4(1H)-quinazolinone

Guidance literature:: Multi-step reaction with 2 steps

1: copper(l) chloride; triethylamine / methanol / 12 h / 20 °C

2: acetic acid / 3 h / 20 °C

With acetic acid; triethylamine; copper(l) chloride; In methanol; 1: |Chan-Lam Coupling;
DOI:10.1039/c7ob02491f