5-Quinolinemethanol, 8-(phenylmethoxy)-

Base Information

Chemical Name:5-Quinolinemethanol, 8-(phenylmethoxy)-
CAS No.:108835-25-2
Molecular Formula:C17H15NO2
Molecular Weight:265.30700
Hs Code.:
Mol file:108835-25-2.mol

Synonyms:8-benzyloxy-5-hydroxymethylquinoleine;5-Quinolinemethanol,8-(phenylmethoxy);8-(benzyloxy)-5-(hydroxymethyl)quinoline;

Suppliers and Price of 5-Quinolinemethanol, 8-(phenylmethoxy)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of 5-Quinolinemethanol, 8-(phenylmethoxy)-

Chemical Property:

PSA：42.35000
LogP:3.30610

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 5-Quinolinemethanol, 8-(phenylmethoxy)-

There total 4 articles about 5-Quinolinemethanol, 8-(phenylmethoxy)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 4053-44-5
5-(hydroxymethyl)-8-hydroxyquinoline

: 100-39-0
benzyl bromide

: 108835-25-2
8-(benzyloxy)-5-(hydroxymethyl)quinoline

Guidance literature:: With sodium hydride; Yield given. Multistep reaction; 1.) DMF, 45 min, 2.) DMF, 4 h;
DOI:10.1021/jm00392a006

Reference yield:

: 148-24-3,24804-14-6
8-quinolinol

: 108835-25-2
8-(benzyloxy)-5-(hydroxymethyl)quinoline

Guidance literature:: Multi-step reaction with 3 steps

1: conc. HCl; HCl gas

2: NH₄OH

3: NaH / dimethylformamide / 16 h

With hydrogenchloride; ammonium hydroxide; sodium hydride; In N,N-dimethyl-formamide; 1: Alkylation / 2: Substitution / 3: Alkylation;
DOI:10.1080/00397910008087242

Reference yield:

: 4053-45-6
5-chloromethyl-8-hydroxyquinoline hydrochloride

: 108835-25-2
8-(benzyloxy)-5-(hydroxymethyl)quinoline

Guidance literature:: Multi-step reaction with 2 steps

1: NH₄OH

2: NaH / dimethylformamide / 16 h

With ammonium hydroxide; sodium hydride; In N,N-dimethyl-formamide; 1: Substitution / 2: Alkylation;
DOI:10.1080/00397910008087242