Benzenecarboximidamide, N-(3,4-dimethylphenyl)-

Base Information

• Chemical Name: Benzenecarboximidamide, N-(3,4-dimethylphenyl)-
• CAS No.: 108837-63-4
• Molecular Formula: C15H16N2
• Molecular Weight: 224.305
• Mol file: 108837-63-4.mol

Synonyms:

Chemical Property of Benzenecarboximidamide, N-(3,4-dimethylphenyl)-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Benzenecarboximidamide, N-(3,4-dimethylphenyl)-

There total 1 articles about Benzenecarboximidamide, N-(3,4-dimethylphenyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.0%

benzonitrile (100-47-0) + 4-amino-o-xylene (95-64-7) → N-(3,4-dimethylphenyl)benzimidamide (108837-63-4)

Guidance literature:

With sodium hydride; In dimethyl sulfoxide; mineral oil; at 0 - 20 ℃; for 16h; Inert atmosphere;

DOI:10.1002/adsc.201600455

Reference yield: 91.0%

N-(3,4-dimethylphenyl)benzimidamide (108837-63-4) + phenylacetaldehyde (122-78-1) → C23H20N2

Guidance literature:

With tert-Butyl peroxybenzoate; iodine; In 1,4-dioxane; at 100 ℃; for 5h; regioselective reaction; Green chemistry;

DOI:10.1039/c7ra01966a

Reference yield: 86.0%

N-(3,4-dimethylphenyl)benzimidamide (108837-63-4) + benzalacetophenone (94-41-7) → (1-(3,4-dimethylphenyl)-2,4-diphenyl-1H-imidazol-5-yl)(phenyl)methanone

Guidance literature:

With iodine; oxygen; iron(III) chloride; In chlorobenzene; at 110 ℃; for 10h; regioselective reaction;

DOI:10.1021/acs.orglett.5b01854

upstream raw materials:

benzonitrile

4-amino-o-xylene

Downstream raw materials:

N-(3,4-dimethyl-phenyl)-benzamide oxime

5,6-dimethyl-2-phenyl-1H-benzo[d]imidazole

5,6-dimethyl-2-phenyl-3,4-dihydroquinazoline

6,7-dimethyl-2-phenyl-3,4-dihydroquinazoline