N-(3-CHLOROBENZYL)-N-(2-[(3-CHLOROBENZYL)AMINO]ETHYL)AMINE

Base Information

• Chemical Name: N-(3-CHLOROBENZYL)-N-(2-[(3-CHLOROBENZYL)AMINO]ETHYL)AMINE
• CAS No.: 108896-77-1
• Molecular Formula: C16H18Cl2N2
• Molecular Weight: 309.23400
• Mol file: 108896-77-1.mol

Synonyms:N,N'-Bis-(3-chloro-benzyl)-ethane-1,2-diamine;N,N'-bis(3-chlorobenzyl)ethylenediamine;

Chemical Property of N-(3-CHLOROBENZYL)-N-(2-[(3-CHLOROBENZYL)AMINO]ETHYL)AMINE

Chemical Property:

• PSA: 24.06000
• LogP: 4.65460

Purity/Quality:

N~1~,N~2~-bis(3-chlorobenzyl)-1,2-ethanediamine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-(3-CHLOROBENZYL)-N-(2-[(3-CHLOROBENZYL)AMINO]ETHYL)AMINE

There total 2 articles about N-(3-CHLOROBENZYL)-N-(2-[(3-CHLOROBENZYL)AMINO]ETHYL)AMINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

N,N'-(ethane-1,2-diyl)bis(1-(3-chlorophenyl)methanimine) (109886-97-7) → N1,N2-bis(3-chlorobenzyl)ethane-1,2-diamine (108896-77-1)

Guidance literature:

With sodium tetrahydroborate; sodium hydroxide; In methanol; dichloromethane; at 15 - 18 ℃; for 5h;

DOI:10.5012/jkcs.2013.57.2.227

Reference yield:

m-Chlorobenzaldehyde (587-04-2) → N1,N2-bis(3-chlorobenzyl)ethane-1,2-diamine (108896-77-1)

Guidance literature:

Multi-step reaction with 2 steps

1: methanol / 3 h / Ambient temperature

2: NaBH₄ / methanol / 3 h / Heating

With sodium tetrahydroborate; In methanol;

Reference yield: 88.0%

benzaldehyde (100-52-7) + N1,N2-bis(3-chlorobenzyl)ethane-1,2-diamine (108896-77-1) → C23H22Cl2N2 (1018786-06-5)

Guidance literature:

In ethanol; water; for 1.5h; Heating;

DOI:10.1016/j.bmc.2007.11.077

upstream raw materials:

N,N'-(ethane-1,2-diyl)bis(1-(3-chlorophenyl)methanimine)

m-Chlorobenzaldehyde

Downstream raw materials:

1,5-Bis-(3-chloro-benzyl)-[1,3,5]triazepane-2,4-dione

1,5-Bis-(3-chloro-benzyl)-4-thioxo-[1,3,5]triazepan-2-one

C₁₇H₁₈Cl₂N₂

C₂₃H₂₂Cl₂N₂