1H-Indole-3-acetaldehyde, 4-(3-methyl-1,3-butadienyl)-1-[(4-methylphenyl)sulfonyl]-, O-methyloxime, (E,E)-

Base Information

Chemical Name:1H-Indole-3-acetaldehyde, 4-(3-methyl-1,3-butadienyl)-1-[(4-methylphenyl)sulfonyl]-, O-methyloxime, (E,E)-
CAS No.:108948-26-1
Molecular Formula:C₂₃H₂₄N₂O₃S
Molecular Weight:408.521
Hs Code.:
Mol file:108948-26-1.mol

Synonyms:

Suppliers and Price of 1H-Indole-3-acetaldehyde, 4-(3-methyl-1,3-butadienyl)-1-[(4-methylphenyl)sulfonyl]-, O-methyloxime, (E,E)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 1H-Indole-3-acetaldehyde, 4-(3-methyl-1,3-butadienyl)-1-[(4-methylphenyl)sulfonyl]-, O-methyloxime, (E,E)-

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 1H-Indole-3-acetaldehyde, 4-(3-methyl-1,3-butadienyl)-1-[(4-methylphenyl)sulfonyl]-, O-methyloxime, (E,E)-

There total 6 articles about 1H-Indole-3-acetaldehyde, 4-(3-methyl-1,3-butadienyl)-1-[(4-methylphenyl)sulfonyl]-, O-methyloxime, (E,E)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: [4-((E)-3-Hydroxy-3-methyl-but-1-enyl)-1-(toluene-4-sulfonyl)-1H-indol-3-yl]-acetaldehyde O-methyl-oxime

: 108948-26-1,108948-35-2
4-(3-methyl-1,3-butadien-1-yl)-3-<2-(methoxyimino)ethyl>-1-tosylindole

Guidance literature:: With acetyl chloride; In pyridine; benzene; for 0.5h; Yield given; Heating;
DOI:10.1021/jo00391a027

Reference yield:

: 115-18-4
2-methyl-3-buten-2-ol

: 108948-26-1,108948-35-2
4-(3-methyl-1,3-butadien-1-yl)-3-<2-(methoxyimino)ethyl>-1-tosylindole

Guidance literature:: Multi-step reaction with 2 steps

1: 85 percent / Et₃N, Pd(OAc)2, (o-tolyl)3P / acetonitrile / 5 h / 100 °C

2: acetyl chloride / pyridine; benzene / 0.5 h / Heating

With palladium diacetate; triethylamine; acetyl chloride; tris-(o-tolyl)phosphine; In pyridine; acetonitrile; benzene;
DOI:10.1021/jo00391a027

Reference yield:

: 90481-83-7
4-bromo-3-iodo-1-tosyl-1H-indole

: 108948-26-1,108948-35-2
4-(3-methyl-1,3-butadien-1-yl)-3-<2-(methoxyimino)ethyl>-1-tosylindole

Guidance literature:: Multi-step reaction with 5 steps

1: 1.) dicyclopentadienylzirconium chloride, 2.) Ni(PPh₃)4 / 1.) benzene, RT, 2 h, 2.) THF, RT, 48 h

2: 1.) BBr₃*SMe₂, 2.) 1 M aq. NaHCO₃ / 1.) CH₂Cl₂, RT, 5 min, 2.) CH₂Cl₂, RT, 2.5 h

3: 66 percent / molecular sieves, O-methylhydroxylamine hydrochloride / pyridine / 1 h / Ambient temperature

4: 85 percent / Et₃N, Pd(OAc)2, (o-tolyl)3P / acetonitrile / 5 h / 100 °C

5: acetyl chloride / pyridine; benzene / 0.5 h / Heating

With palladium diacetate; molecular sieve; zirconocene dichloride; boron tribromide-dimethyl sulfide complex; tetrakis(triphenylphosphine)nickel⁽⁰⁾; N-methoxylamine hydrochloride; sodium hydrogencarbonate; triethylamine; acetyl chloride; tris-(o-tolyl)phosphine; In pyridine; acetonitrile; benzene;
DOI:10.1021/jo00391a027