2-[Chloro-(6-methoxy-2-methylpyrimidin-4-yl)methyl]-5-(hydroxymethyl)oxolane-3,4-diol

Base Information

Chemical Name:2-[Chloro-(6-methoxy-2-methylpyrimidin-4-yl)methyl]-5-(hydroxymethyl)oxolane-3,4-diol
CAS No.:85922-47-0
Molecular Formula:C₁₂H₁₇ClN₂O₅
Molecular Weight:304.73
Hs Code.:
NSC Number:370605,370473
DSSTox Substance ID:DTXSID201006451

Synonyms:85879-00-1;NSC370473;DTXSID201006451;NSC370605;NSC-370473;NSC-370605;2,5-Anhydro-1-chloro-1-deoxy-1-(6-methoxy-2-methylpyrimidin-4-yl)hexitol;85922-47-0

Suppliers and Price of 2-[Chloro-(6-methoxy-2-methylpyrimidin-4-yl)methyl]-5-(hydroxymethyl)oxolane-3,4-diol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 2-[Chloro-(6-methoxy-2-methylpyrimidin-4-yl)methyl]-5-(hydroxymethyl)oxolane-3,4-diol

Chemical Property:

Vapor Pressure:8.68E-12mmHg at 25°C
Boiling Point:523.5°C at 760 mmHg
Flash Point:270.4°C
Density:1.454g/cm³
XLogP3:-0.2
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:4
Exact Mass:304.0825993
Heavy Atom Count:20
Complexity:324

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=NC(=CC(=N1)OC)C(C2C(C(C(O2)CO)O)O)Cl

Technology Process of 2-[Chloro-(6-methoxy-2-methylpyrimidin-4-yl)methyl]-5-(hydroxymethyl)oxolane-3,4-diol

There total 2 articles about 2-[Chloro-(6-methoxy-2-methylpyrimidin-4-yl)methyl]-5-(hydroxymethyl)oxolane-3,4-diol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 67-56-1
methanol

: 54503-64-9,54503-65-0
2,3-O-isopropylidene-5-O-trityl-D-ribofuranose

: 74181-44-5
triphenylphosphorane

: 85879-00-1,85922-47-0
(2S,3R,4S,5R)-2-[Chloro-(6-methoxy-2-methyl-pyrimidin-4-yl)-methyl]-5-hydroxymethyl-tetrahydro-furan-3,4-diol

: 85879-00-1,85922-47-0
(2R,3R,4S,5R)-2-[Chloro-(6-methoxy-2-methyl-pyrimidin-4-yl)-methyl]-5-hydroxymethyl-tetrahydro-furan-3,4-diol

Guidance literature:: With hydrogenchloride; Yield given. Multistep reaction. Yields of byproduct given; 1.) acetonitrile, reflux, 9 h, 2.) room temperature, 3 h;

Reference yield:

: 67-56-1
methanol

: 54503-64-9,54503-65-0
2,3-O-isopropylidene-5-O-trityl-D-ribofuranose

: 74181-44-5
triphenylphosphorane

: 85879-00-1,85922-47-0
(2S,3R,4S,5R)-2-[Chloro-(6-methoxy-2-methyl-pyrimidin-4-yl)-methyl]-5-hydroxymethyl-tetrahydro-furan-3,4-diol

: 85879-00-1,85922-47-0
(2R,3R,4S,5R)-2-[Chloro-(6-methoxy-2-methyl-pyrimidin-4-yl)-methyl]-5-hydroxymethyl-tetrahydro-furan-3,4-diol

Guidance literature:: With hydrogenchloride; Yield given. Multistep reaction. Yields of byproduct given; 1.) acetonitrile, reflux, 9 h, 2.) room temperature, 3 h;