2,3-Bis{[tert-butyl(dimethyl)silyl]oxy}-4-methoxybenzaldehyde

Base Information

Chemical Name:2,3-Bis{[tert-butyl(dimethyl)silyl]oxy}-4-methoxybenzaldehyde
CAS No.:109971-66-6
Molecular Formula:C20H36O4Si2
Molecular Weight:396.674
Hs Code.:
DSSTox Substance ID:DTXSID00552453
Nikkaji Number:J2.721.964K
Wikidata:Q82432715
Mol file:109971-66-6.mol

Synonyms:109971-66-6;SCHEMBL5139277;DTXSID00552453;2,3-Bis{[tert-butyl(dimethyl)silyl]oxy}-4-methoxybenzaldehyde;2,3-Bis-(tert-butyl-dimethyl-silanyloxy)-4-methoxy-benzaldehyde

Suppliers and Price of 2,3-Bis{[tert-butyl(dimethyl)silyl]oxy}-4-methoxybenzaldehyde

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 1 raw suppliers

Chemical Property of 2,3-Bis{[tert-butyl(dimethyl)silyl]oxy}-4-methoxybenzaldehyde

Chemical Property:

Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:8
Exact Mass:396.21521269
Heavy Atom Count:26
Complexity:477

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)[Si](C)(C)OC1=C(C=CC(=C1O[Si](C)(C)C(C)(C)C)OC)C=O

Technology Process of 2,3-Bis{[tert-butyl(dimethyl)silyl]oxy}-4-methoxybenzaldehyde

There total 3 articles about 2,3-Bis{[tert-butyl(dimethyl)silyl]oxy}-4-methoxybenzaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 4055-69-0
2,3-dihydroxy-4-methoxybenzaldehyde

: 109971-66-6
2,3-bis<(tert-butyldimethylsilyl)oxy>-4-methoxybenzaldehyde

Guidance literature:: With dmap; triethylamine; In N,N-dimethyl-formamide; at 20 ℃; for 18h; Inert atmosphere;
DOI:10.1016/j.bmc.2012.01.010

Reference yield: 84.0%

: 4055-69-0
2,3-dihydroxy-4-methoxybenzaldehyde

: 18162-48-6
tert-butyldimethylsilyl chloride

: 109971-66-6
2,3-bis<(tert-butyldimethylsilyl)oxy>-4-methoxybenzaldehyde

Guidance literature:: With N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; at 20 ℃; for 3.08333h;
DOI:10.1021/np800608c

Reference yield:

: 2103-57-3
2,3,4-trimethoxybenzaldehyde

: 109971-66-6
2,3-bis<(tert-butyldimethylsilyl)oxy>-4-methoxybenzaldehyde

Guidance literature:: Multi-step reaction with 2 steps

1: boron trichloride / dichloromethane / 20 h / 20 °C / Inert atmosphere

2: dmap; triethylamine / N,N-dimethyl-formamide / 18 h / 20 °C / Inert atmosphere

With dmap; boron trichloride; triethylamine; In dichloromethane; N,N-dimethyl-formamide;
DOI:10.1016/j.bmc.2012.01.010