N-(m-Tolyl)hydroxylamine

Base Information

• Chemical Name: N-(m-Tolyl)hydroxylamine
• CAS No.: 620-25-7
• Molecular Formula: C7H9 N O
• Molecular Weight: 123.155
• Hs Code.: 2928000090
• DSSTox Substance ID: DTXSID80211036
• Nikkaji Number: J134.587G
• Wikidata: Q83085886
• Mol file: 620-25-7.mol

Synonyms:N-(m-Tolyl)hydroxylamine;N-(3-Methylphenyl)hydroxylamine;620-25-7;m-Tolylhydroxylamine;CCRIS 3487;3-(Hydroxyamino)toluene;3-Methylphenylhydroxylamine;META-TOLYLHYDROXYLAMINE;N-Hydroxy-3-methylbenzenamine;Benzenamine, N-hydroxy-3-methyl-;BRN 1931521;Hydroxylamine, N-(m-tolyl)-;Benzenamine, N-hydroxy-3-methyl- (9CI);3-15-00-00017 (Beilstein Handbook Reference);m-Toluyl-hydroxylamin;N-m-tolyl-hydroxylamine;SCHEMBL849882;DTXSID80211036;N-(3-methylphenyl) hydroxylamine;LS-77505;EN300-7456949

Chemical Property of N-(m-Tolyl)hydroxylamine

Chemical Property:

• Vapor Pressure: 0.0384mmHg at 25°C
• Boiling Point: 229.7°C at 760 mmHg
• Flash Point: 116°C
• PSA: 32.26000
• Density: 1.159g/cm³
• LogP: 1.86910
• XLogP3: 2.1
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 123.068413911
• Heavy Atom Count: 9
• Complexity: 85

Purity/Quality:

98%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC(=CC=C1)NO

Technology Process of N-(m-Tolyl)hydroxylamine

There total 13 articles about N-(m-Tolyl)hydroxylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

1-methyl-3-nitrobenzene (99-08-1) → N-(3-methylphenyl)hydroxylamine (620-25-7)

Guidance literature:

With methyldiazene; In acetonitrile; at 28 ℃; for 1.33333h; Irradiation; Sealed tube; Inert atmosphere;

DOI:10.1021/acs.orglett.0c01367

Reference yield: 90.0%

C14H12N2O3 (1062320-37-9) + malononitrile (109-77-3) → 4-Nitrobenzylidenemalononitrile (2700-23-4) + N-(3-methylphenyl)hydroxylamine (620-25-7)

Guidance literature:

With sodium dodecyl-sulfate; In water; at 25 - 30 ℃; for 0.166667h;

Reference yield: 85.0%

C16H15NO + ethyl 2-cyanoacetate (105-56-6) → N-(3-methylphenyl)hydroxylamine (620-25-7) + (2E,4E)-2-cyano-5-phenyl-2,4-pentadienoic acid ethyl ester (41109-95-9)

Guidance literature:

With sodium dodecyl-sulfate; In water; at 25 - 30 ℃; for 0.25h;

upstream raw materials:

1-methyl-3-nitrobenzene

GLUTATHIONE

3-nitrosotoluene

acetic acid

Downstream raw materials:

N,N'-bis(3-methylphenyl)-diazene N-oxide

5-methyl-2-m-tolyl-isoxazol-3-one

N-m-tolyl-2-furylacrylohydroxamic acid

α-amino-α-carbethoxy-N-(3-methylphenyl)-nitrone