Technology Process of Morpholine, 4-[(2-phenylethenyl)sulfonyl]-, (Z)-
There total 6 articles about Morpholine, 4-[(2-phenylethenyl)sulfonyl]-, (Z)- which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 50percent aq. NaOH, Bu4N(1+)*HSO4(1-), HMPT
2: Br2 / CCl4 / 2.5 h / Heating
3: t-BuOK / dioxane; 2-methyl-propan-2-ol / 3 h / Ambient temperature
4: aq. NaPO2H2 / 10percent Pd/C / ethanol / 15 h / Heating
With
N,N,N,N,N,N-hexamethylphosphoric triamide; sodium hydroxide; sodium hypophosphite; potassium tert-butylate; bromine; tetra(n-butyl)ammonium hydrogensulfate;
palladium on activated charcoal;
In
1,4-dioxane; tetrachloromethane; ethanol; tert-butyl alcohol;
DOI:10.1021/jm00395a010
- Guidance literature:
-
Multi-step reaction with 3 steps
1: Br2 / CCl4 / 2.5 h / Heating
2: t-BuOK / dioxane; 2-methyl-propan-2-ol / 3 h / Ambient temperature
3: aq. NaPO2H2 / 10percent Pd/C / ethanol / 15 h / Heating
With
sodium hypophosphite; potassium tert-butylate; bromine;
palladium on activated charcoal;
In
1,4-dioxane; tetrachloromethane; ethanol; tert-butyl alcohol;
DOI:10.1021/jm00395a010
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 1.) Br2, 2.) NEt3 / 1.) CCl4, RT, 2.) Et2O, -5 deg C
2: CH2Cl2 / 3 h / Ambient temperature
3: t-BuOK / dioxane; 2-methyl-propan-2-ol / 3 h / Ambient temperature
4: aq. NaPO2H2 / 10percent Pd/C / ethanol / 15 h / Heating
With
sodium hypophosphite; potassium tert-butylate; bromine; triethylamine;
palladium on activated charcoal;
In
1,4-dioxane; ethanol; dichloromethane; tert-butyl alcohol;
DOI:10.1021/jm00395a010
