Ethyl 6-ethyl-3-iodo-2-methoxypiperidine-1-carboxylate

Base Information

Chemical Name:Ethyl 6-ethyl-3-iodo-2-methoxypiperidine-1-carboxylate
CAS No.:111054-41-2
Molecular Formula:C₁₁H₂₀INO₃
Molecular Weight:341.189
Hs Code.:
DSSTox Substance ID:DTXSID30548526
Mol file:111054-41-2.mol

Synonyms:111054-41-2;Ethyl 6-ethyl-3-iodo-2-methoxypiperidine-1-carboxylate;DTXSID30548526

Suppliers and Price of Ethyl 6-ethyl-3-iodo-2-methoxypiperidine-1-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Ethyl 6-ethyl-3-iodo-2-methoxypiperidine-1-carboxylate

Chemical Property:

XLogP3:3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:341.04879
Heavy Atom Count:16
Complexity:237

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCC1CCC(C(N1C(=O)OCC)OC)I

Technology Process of Ethyl 6-ethyl-3-iodo-2-methoxypiperidine-1-carboxylate

There total 3 articles about Ethyl 6-ethyl-3-iodo-2-methoxypiperidine-1-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

: 67-56-1
methanol

: 111054-56-9
2-Ethyl-3,4-dihydro-2H-pyridine-1-carboxylic acid ethyl ester

: 111054-41-2
6-Ethyl-3-iodo-2-methoxy-piperidine-1-carboxylic acid ethyl ester

Guidance literature:: With ammonium iodide; at 15 ℃; Pt-electrodes, 2 V, 4.6 F/mol;
DOI:10.1055/s-1987-27901

Reference yield:

: 82902-42-9
ethyl 2-ethylpiperidine-1-carboxylate

: 111054-41-2
6-Ethyl-3-iodo-2-methoxy-piperidine-1-carboxylic acid ethyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: tetraethylammonium tosylate / 15 °C / carbon electrodes, 200 mA, 8-15V

2: NH₄Br / 2 h / 100 - 130 °C

3: 74 percent / NH₄I / 15 °C / Pt-electrodes, 2 V, 4.6 F/mol

With ammonium iodide; tetraethylammonium tosylate; ammonium bromide;
DOI:10.1055/s-1987-27901

Reference yield:

: 111054-60-5
2-Ethyl-6-methoxy-piperidine-1-carboxylic acid ethyl ester

: 111054-41-2
6-Ethyl-3-iodo-2-methoxy-piperidine-1-carboxylic acid ethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: NH₄Br / 2 h / 100 - 130 °C

2: 74 percent / NH₄I / 15 °C / Pt-electrodes, 2 V, 4.6 F/mol

With ammonium iodide; ammonium bromide;
DOI:10.1055/s-1987-27901