Imidazo[4,5-d]imidazole-2,5(1H,3H)-dione, 1,3,4,6-tetrakis[(4-chlorobutoxy)methyl]tetrahydro-3a,6a-diphenyl-, cis-

Base Information

• Chemical Name: Imidazo[4,5-d]imidazole-2,5(1H,3H)-dione, 1,3,4,6-tetrakis[(4-chlorobutoxy)methyl]tetrahydro-3a,6a-diphenyl-, cis-
• CAS No.: 111380-79-1
• Molecular Formula: C36H50Cl4N4O6
• Molecular Weight: 776.628
• Mol file: 111380-79-1.mol

Synonyms:

Chemical Property of Imidazo[4,5-d]imidazole-2,5(1H,3H)-dione, 1,3,4,6-tetrakis[(4-chlorobutoxy)methyl]tetrahydro-3a,6a-diphenyl-, cis-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Imidazo[4,5-d]imidazole-2,5(1H,3H)-dione, 1,3,4,6-tetrakis[(4-chlorobutoxy)methyl]tetrahydro-3a,6a-diphenyl-, cis-

There total 2 articles about Imidazo[4,5-d]imidazole-2,5(1H,3H)-dione, 1,3,4,6-tetrakis[(4-chlorobutoxy)methyl]tetrahydro-3a,6a-diphenyl-, cis- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

4-Chloro-1-butanol (928-51-8) + 1,3,4,6-tetrakis(hydroxymethyl)tetrahydro-3a,6a-diphenylimidazo<4,5-d>imidazole-2,5(1H,3H)-dione (101241-22-9) → 1,3,4,6-tetrakis(6-chloro-2-oxahexyl)tetrahydro-3a,6a-diphenylimidazo<4,5-d>imidazole-2,5(1H,3H)-dione (111380-79-1)

Guidance literature:

With toluene-4-sulfonic acid; In toluene; for 60h; Heating;

DOI:10.1021/ja00209a027

Reference yield:

3a,6a-diphenylglycoluril (101241-21-8) → 1,3,4,6-tetrakis(6-chloro-2-oxahexyl)tetrahydro-3a,6a-diphenylimidazo<4,5-d>imidazole-2,5(1H,3H)-dione (111380-79-1)

Guidance literature:

Multi-step reaction with 2 steps

1: 82 percent / 1M aqueous NaOH / dimethylsulfoxide / 16 h / Ambient temperature; pH = 9

2: 79 percent / p-toluenesulfonic acid monohydrate / toluene / 60 h / Heating

With sodium hydroxide; toluene-4-sulfonic acid; In dimethyl sulfoxide; toluene;

DOI:10.1021/ja00209a027

Reference yield:

imidazolyl sodium (5587-42-8) + 1,3,4,6-tetrakis(6-chloro-2-oxahexyl)tetrahydro-3a,6a-diphenylimidazo<4,5-d>imidazole-2,5(1H,3H)-dione (111380-79-1) → 1,3,4,6-tetrakis<6-(1-imidazolyl)-2-oxahexyl>tetrahydro-3a,6a-diphenylimidazo<4,5-d>imidazole-2,5(1H,3H)-dione (111380-80-4)

Guidance literature:

In N,N-dimethyl-formamide; at 80 ℃; for 16h;

DOI:10.1021/ja00209a027

upstream raw materials:

4-Chloro-1-butanol

1,3,4,6-tetrakis(hydroxymethyl)tetrahydro-3a,6a-diphenylimidazo<4,5-d>imidazole-2,5(1H,3H)-dione

3a,6a-diphenylglycoluril

Downstream raw materials:

1,3,4,6-tetrakis<6-(1-imidazolyl)-2-oxahexyl>tetrahydro-3a,6a-diphenylimidazo<4,5-d>imidazole-2,5(1H,3H)-dione