Benzoic acid, 4-methoxy-2-[3-methoxy-4-(methoxycarbonyl)-5-methylphenoxy]-6-meth yl-, phenylmethyl ester

Base Information

• Chemical Name: Benzoic acid, 4-methoxy-2-[3-methoxy-4-(methoxycarbonyl)-5-methylphenoxy]-6-meth yl-, phenylmethyl ester
• CAS No.: 111699-21-9
• Molecular Formula: C26H26O7
• Molecular Weight: 450.488
• Mol file: 111699-21-9.mol

Synonyms:

Chemical Property of Benzoic acid, 4-methoxy-2-[3-methoxy-4-(methoxycarbonyl)-5-methylphenoxy]-6-meth yl-, phenylmethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Benzoic acid, 4-methoxy-2-[3-methoxy-4-(methoxycarbonyl)-5-methylphenoxy]-6-meth yl-, phenylmethyl ester

There total 5 articles about Benzoic acid, 4-methoxy-2-[3-methoxy-4-(methoxycarbonyl)-5-methylphenoxy]-6-meth yl-, phenylmethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

benzyl 4-hydroxy-2-(3'-hydroxy-4'-methoxycarbonyl-5'-methylphenoxy)-6-methylbenzoate (111699-20-8) + dimethyl sulfate (77-78-1) → benzyl 4-methoxy-2-(3'-methoxy-4'-methoxycarbonyl-5'-methylphenoxy)-6-methylbenzoate (111699-21-9)

Guidance literature:

With potassium carbonate; In acetone; for 27h; Heating;

Reference yield:

methyl 4-O-benzyllecanorate (61158-11-0) → benzyl 4-methoxy-2-(3'-methoxy-4'-methoxycarbonyl-5'-methylphenoxy)-6-methylbenzoate (111699-21-9)

Guidance literature:

Multi-step reaction with 4 steps

1: 87 percent / potassium carbonate / dimethylsulfoxide / 2 h / Ambient temperature

2: 97 percent / H₂ / 10percent Pd/C / ethyl acetate / 2 h

3: 60 percent / ethyl acetate / 0.08 h / Ambient temperature

4: 90 percent / potassium carbonate / acetone / 27 h / Heating

With hydrogen; potassium carbonate; palladium on activated charcoal; In dimethyl sulfoxide; ethyl acetate; acetone;

Reference yield:

4-benzyloxy-2-(3'-hydroxy-4'-methoxycarbonyl-5'-methylphenoxy)-6-methylbenzoic acid (111699-18-4) → benzyl 4-methoxy-2-(3'-methoxy-4'-methoxycarbonyl-5'-methylphenoxy)-6-methylbenzoate (111699-21-9)

Guidance literature:

Multi-step reaction with 3 steps

1: 97 percent / H₂ / 10percent Pd/C / ethyl acetate / 2 h

2: 60 percent / ethyl acetate / 0.08 h / Ambient temperature

3: 90 percent / potassium carbonate / acetone / 27 h / Heating

With hydrogen; potassium carbonate; palladium on activated charcoal; In ethyl acetate; acetone;

upstream raw materials:

benzyl 4-hydroxy-2-(3'-hydroxy-4'-methoxycarbonyl-5'-methylphenoxy)-6-methylbenzoate

dimethyl sulfate

methyl 4-O-benzyllecanorate

4-benzyloxy-2-(3'-hydroxy-4'-methoxycarbonyl-5'-methylphenoxy)-6-methylbenzoic acid

Downstream raw materials:

schizopeltic acid

Refernces