Carbazole, 3-(2,2-diethoxyethyliminomethyl)-1,4-dimethyl-

Base Information

• Chemical Name: Carbazole, 3-(2,2-diethoxyethyliminomethyl)-1,4-dimethyl-
• CAS No.: 18073-23-9
• Molecular Formula: C21H26N2O2
• Molecular Weight: 338.45
• Hs Code.: 2933990090
• NSC Number: 79487
• UNII: DGH48T4PY6
• Nikkaji Number: J48.442C
• Mol file: 18073-23-9.mol

Synonyms:18073-23-9;NSC 79487;3-(2,4-dimethylcarbazole;CARBAZOLE, 3-(2,2-DIETHOXYETHYLIMINOMETHYL)-1,4-DIMETHYL-;BRN 1548041;DGH48T4PY6;3-(2,2-Diethoxyethyliminomethyl)-1,4-dimethylcarbazole;N-(2,2-diethoxyethyl)-1-(1,4-dimethyl-9H-carbazol-3-yl)methanimine;NSC-79487;3-[N-(2,2-Diethoxyethyl)formimidoyl]-1,4-dimethyl-9H-carbazole;Acetaldehyde, (((1,4-dimethylcarbazol-3-yl)methylene)amino)-, diethyl acetal;Acetaldehyde, [[(1,4-dimethylcarbazol-3-yl)methylene]amino]-, diethyl acetal;NSC79487;UNII-DGH48T4PY6;NCIOpen2_008676;SCHEMBL15521400;LS-51746;WLN: T B656 HMJ C1 D1UN1YO2&O2 F1;Carbazole,2-diethoxyethyliminomethyl)-1,4-dimethyl-;Acetaldehyde,4-dimethylcarbazol-3-yl)methylene]amino]-, diethyl acetal;ETHANAMINE, N-((1,4-DIMETHYL-9H-CARBAZOL-3-YL)METHYLENE)-2,2-DIETHOXY-;N-((1,4-DIMETHYL-9H-CARBAZOL-3-YL)METHYLENE)-2,2-DIETHOXYETHANAMINE

Chemical Property of Carbazole, 3-(2,2-diethoxyethyliminomethyl)-1,4-dimethyl-

Chemical Property:

• Vapor Pressure: 4.91E-10mmHg at 25°C
• Boiling Point: 510.5°C at 760 mmHg
• Flash Point: 262.6°C
• PSA: 46.61000
• Density: 1.11g/cm³
• LogP: 4.75590
• XLogP3: 4.3
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 7
• Exact Mass: 338.199428076
• Heavy Atom Count: 25
• Complexity: 436

Purity/Quality:

85.0-99.8% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCOC(CN=CC1=C(C2=C(C(=C1)C)NC3=CC=CC=C32)C)OCC

Technology Process of Carbazole, 3-(2,2-diethoxyethyliminomethyl)-1,4-dimethyl-

There total 6 articles about Carbazole, 3-(2,2-diethoxyethyliminomethyl)-1,4-dimethyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1,4-dimethylcarbazole-3-carboxaldehyde (14501-66-7) + 2,2-diethoxy-ethanamine (645-36-3) → 3-(2,2-diethoxyethyliminomethyl)-1,4-dimethylcarbazole (18073-23-9)

Guidance literature:

In benzene; for 2h; Reflux;

DOI:10.1016/j.tetlet.2010.02.125

Reference yield:

indole (120-72-9) → 3-(2,2-diethoxyethyliminomethyl)-1,4-dimethylcarbazole (18073-23-9)

Guidance literature:

Multi-step reaction with 2 steps

1.1: toluene-4-sulfonic acid / ethanol / 2 h / Reflux

2.1: trichlorophosphate / chlorobenzene / 6.5 h / 131 °C

2.2: 4 h / 110 °C

With toluene-4-sulfonic acid; trichlorophosphate; In ethanol; chlorobenzene;

DOI:10.1002/jhet.598

Reference yield:

1,4-dimethyl-9H-carbazole (18028-55-2) + 2,2-diethoxy-ethanamine (645-36-3) + N,N-dimethyl-formamide (68-12-2,33513-42-7) → 3-(2,2-diethoxyethyliminomethyl)-1,4-dimethylcarbazole (18073-23-9) + 6-(2,2-diethoxyethyliminomethyl)-1,4-dimethylcarbazole (1326776-28-6)

Guidance literature:

1,4-dimethyl-9H-carbazole; N,N-dimethyl-formamide; With trichlorophosphate; In chlorobenzene; at 131 ℃; for 6.5h;

2,2-diethoxy-ethanamine; at 110 ℃; for 4h;

DOI:10.1002/jhet.598

upstream raw materials:

1,4-dimethylcarbazole-3-carboxaldehyde

2,2-diethoxy-ethanamine

indole

9-formyl-1,4-dimethylcarbazole

Downstream raw materials:

N-(1,4-dimethylcarbazol-3-ylmethyl) aminoacetaldehyde diethyl acetal

9-hydroxyellipticine

N-(2,2-diethoxyethyl)-N-(1,4-dimethyl-9H-carbazol-3-ylmethyl)-4-methylbenzenesulfonamide

ellipticine