N-(3-Amino-2,6-dimethylphenyl)-2-(diethylamino)acetamide

Base Information

Chemical Name:N-(3-Amino-2,6-dimethylphenyl)-2-(diethylamino)acetamide
CAS No.:39942-50-2
Molecular Formula:C14H23N3O
Molecular Weight:249.356
Hs Code.:
NSC Number:34019
UNII:V9Z6FQ7AUP
DSSTox Substance ID:DTXSID20192991
Wikidata:Q83065691
Mol file:39942-50-2.mol

Synonyms:3-Amino Lidocaine;39942-50-2;N-(3-Amino-2,6-dimethylphenyl)-2-(diethylamino)acetamide;NSC34019;NSC 34019;V9Z6FQ7AUP;NSC-34019;UNII-V9Z6FQ7AUP;2-Diethylamino-3'-amino-2',6'-acetoxylidide;SCHEMBL4454131;DTXSID20192991;AKOS030239969;FT-0661872;2-Diethylamino-3?-amino-2?,6?-acetoxylidide;N-(3-amino-2,6-dimethyl-phenyl)-2-(diethylamino)acetamide;Acetamide, N-(3-amino-2,6-dimethylphenyl)-2-(diethylamino)-

Suppliers and Price of N-(3-Amino-2,6-dimethylphenyl)-2-(diethylamino)acetamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
3-Amino Lidocaine
100mg
$ 418.00

TRC
3-AminoLidocaine
1g
$ 950.00

Medical Isotopes, Inc.
3-AminoLidocaine
1 g
$ 1960.00

Biosynth Carbosynth
3-Amino lidocaine
1 g
$ 1310.40

Biosynth Carbosynth
3-Amino lidocaine
250 mg
$ 397.50

Biosynth Carbosynth
3-Amino lidocaine
100 mg
$ 219.00

Biosynth Carbosynth
3-Amino lidocaine
50 mg
$ 120.50

Biosynth Carbosynth
3-Amino lidocaine
500 mg
$ 720.00

American Custom Chemicals Corporation
3-AMINO LIDOCAINE 95.00%
5MG
$ 504.94

AK Scientific
N-(3-Amino-2,6-dimethylphenyl)-2-(diethylamino)acetamide
1g
$ 1819.00

Total 10 raw suppliers

Chemical Property of N-(3-Amino-2,6-dimethylphenyl)-2-(diethylamino)acetamide

Chemical Property:

Vapor Pressure:1.47E-06mmHg at 25°C
Refractive Index:1.579
Boiling Point:398.5 °C at 760 mmHg
Flash Point:194.8 °C
PSA：58.36000
Density:1.081 g/cm³
LogP:2.82010
Storage Temp.:Refrigerator
Solubility.:DMSO, Methanol
XLogP3:1.6
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:5
Exact Mass:249.184112366
Heavy Atom Count:18
Complexity:266

Purity/Quality:

99% ^*data from raw suppliers

3-Amino Lidocaine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCN(CC)CC(=O)NC1=C(C=CC(=C1C)N)C

Technology Process of N-(3-Amino-2,6-dimethylphenyl)-2-(diethylamino)acetamide

There total 4 articles about N-(3-Amino-2,6-dimethylphenyl)-2-(diethylamino)acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 39942-49-9
2-diethylamino-N-(2,6-dimethyl-3-nitro-phenyl)-acetamide

: 39942-50-2
N-(3-amino-2,6-dimethylphenyl)-2-(diethylamino)acetamide

Guidance literature:: With hydrogenchloride; iron; In water; at 5 - 30 ℃; for 1h;

Reference yield:

: 137-58-6
2-diethylamino-N-(2,6-dimethylphenyl)-acetamide

: 39942-50-2
N-(3-amino-2,6-dimethylphenyl)-2-(diethylamino)acetamide

: 27951-88-8
N-(4-amino-2,6-dimethylphenyl)-2-(diethylamino)acetamide

Guidance literature:: 2-diethylamino-N-(2,6-dimethylphenyl)-acetamide; With sulfuric acid; hydroxylamine hydrochloride; In acetonitrile; at 25 ℃; for 0.166667h;

With hydrogenchloride; titanium(III) chloride; In water; acetonitrile; at 25 ℃; Overall yield = 80 percent; Overall yield = 199 mg; Inert atmosphere; Sealed tube;
DOI:10.1021/acs.orglett.0c00598

Reference yield:

: 137-58-6
2-diethylamino-N-(2,6-dimethylphenyl)-acetamide

: 39942-50-2
N-(3-amino-2,6-dimethylphenyl)-2-(diethylamino)acetamide

Guidance literature:: Multi-step reaction with 2 steps

1: sulfuric acid; nitric acid / water / 0.75 h / 0 - 25 °C

2: hydrogenchloride; iron / water / 1 h / 5 - 30 °C

With hydrogenchloride; sulfuric acid; nitric acid; iron; In water;