3-Nitro Lidocaine

Base Information

• Chemical Name: 3-Nitro Lidocaine
• CAS No.: 39942-49-9
• Molecular Formula: C14H21N3O3
• Molecular Weight: 279.339
• Mol file: 39942-49-9.mol

Synonyms:3-Nitro Lidocaine;2-Diethylamino-3'-nitro-2',6'-acetoxylidide;|A-Diethylamino-3-nitro-2,6-dimethylacetanilide;

Chemical Property of 3-Nitro Lidocaine

Chemical Property:

• Melting Point: 49-55?C
• PSA: 81.65000
• LogP: 3.66460
• Storage Temp.: Refrigerator
• Solubility.: Chloroform (Slightly), Methanol (Slightly)

Purity/Quality:

97% ^*data from raw suppliers

3-Nitro Lidocaine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 3-Nitro Lidocaine ia a Lidocaine analogue.

Technology Process of 3-Nitro Lidocaine

There total 3 articles about 3-Nitro Lidocaine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

2-diethylamino-N-(2,6-dimethylphenyl)-acetamide (137-58-6) → 2-diethylamino-N-(2,6-dimethyl-3-nitro-phenyl)-acetamide (39942-49-9)

Guidance literature:

With sulfuric acid; nitric acid; In water; at 0 - 25 ℃; for 0.75h;

Reference yield: 71.0%

→ 2-diethylamino-N-(2,6-dimethyl-3-nitro-phenyl)-acetamide (39942-49-9)

Guidance literature:

With 2-nitrobenzo[d]isothiazol-3(2H)-one 1,1-dioxide; at 55 - 60 ℃; for 19h; Inert atmosphere; Sealed tube;

Reference yield:

concentrated sodium hydroxide + α-chloro-3-nitro-2,6-dimetylacetanilide + diethylamine (109-89-7) → 2-diethylamino-N-(2,6-dimethyl-3-nitro-phenyl)-acetamide (39942-49-9)

Guidance literature:

In chloroform; benzene;

upstream raw materials:

diethylamine

2-diethylamino-N-(2,6-dimethylphenyl)-acetamide

Downstream raw materials:

N-(3-amino-2,6-dimethylphenyl)-2-(diethylamino)acetamide

2-diethylamino-N-[2,6-dimethyl-3-(4-phenyl-butylamino)-phenyl]-acetamide

N-[3-(3-benzyl-ureido)-2,6-dimethyl-phenyl]-2-diethylamino-acetamide

2-diethylamino-N-[2,6-dimethyl-3-tridecylamino-phenyl]-acetamide

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