2-Fluoro-6-(trifluoromethyl)quinoxaline

Base Information

Chemical Name:2-Fluoro-6-(trifluoromethyl)quinoxaline
CAS No.:112080-08-7
Molecular Formula:C₉H₄F₄N₂
Molecular Weight:216.138
Hs Code.:
DSSTox Substance ID:DTXSID70553659
Wikidata:Q82434301

Synonyms:2-Fluoro-6-(trifluoromethyl)quinoxaline;112080-08-7;DTXSID70553659

Suppliers and Price of 2-Fluoro-6-(trifluoromethyl)quinoxaline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
2-Fluoro-6-(trifluoromethyl)quinoxaline 95+%
1g
$ 608.00

Chemenu
2-fluoro-6-(trifluoromethyl)quinoxaline 95%
1g
$ 574.00

Alichem
2-Fluoro-6-(trifluoromethyl)quinoxaline
1g
$ 504.90

Total 1 raw suppliers

Chemical Property of 2-Fluoro-6-(trifluoromethyl)quinoxaline

Chemical Property:

PSA：25.78000
LogP:2.78770
XLogP3:2.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:0
Exact Mass:216.03106078
Heavy Atom Count:15
Complexity:231

Purity/Quality:: 2-Fluoro-6-(trifluoromethyl)quinoxaline 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC2=NC(=CN=C2C=C1C(F)(F)F)F

Technology Process of 2-Fluoro-6-(trifluoromethyl)quinoxaline

There total 3 articles about 2-Fluoro-6-(trifluoromethyl)quinoxaline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 58.0%

: 41213-32-5
2-chloro-6-(trifluoromethyl)-quinoxaline

: 112080-08-7
2-Fluoro-6-trifluoromethyl-quinoxaline

Guidance literature:: With 18-crown-6 ether; 4 A molecular sieve; cesium fluoride; In tetrahydrofuran; for 20h; Ambient temperature;
DOI:10.3987/R-1987-05-1215

Reference yield:

: 55687-18-8
6-(trifluoromethyl)-2(1H)-quinoxalinone

: 112080-08-7
2-Fluoro-6-trifluoromethyl-quinoxaline

: 2-Difluoromethoxy-6-trifluoromethyl-quinoxaline

: 1-Difluoromethyl-6-trifluoromethyl-1H-quinoxalin-2-one

Guidance literature:: With Chlorodifluoromethane; potassium carbonate; In N,N-dimethyl-formamide; at 90 ℃; for 1h; Yield given. Yields of byproduct given;
DOI:10.1016/S0022-1139(00)80339-5

Reference yield:

: 75-45-6
Chlorodifluoromethane

: 55687-18-8
6-(trifluoromethyl)-2(1H)-quinoxalinone

: 112080-08-7
2-Fluoro-6-trifluoromethyl-quinoxaline

: 2-Difluoromethoxy-6-trifluoromethyl-quinoxaline

: 1-Difluoromethyl-6-trifluoromethyl-1H-quinoxalin-2-one

Guidance literature:: With potassium carbonate; In N,N-dimethyl-formamide; at 90 ℃; for 1h; Yield given. Yields of byproduct given;
DOI:10.1016/S0022-1139(00)80339-5