n-(4-Benzoylpyridin-3-yl)-2,2-dimethylpropanamide

Base Information

Chemical Name:n-(4-Benzoylpyridin-3-yl)-2,2-dimethylpropanamide
CAS No.:112175-38-9
Molecular Formula:C17H18N2O2
Molecular Weight:282.342
Hs Code.:
DSSTox Substance ID:DTXSID40550791
Wikidata:Q82430235

Synonyms:112175-38-9;n-(4-benzoylpyridin-3-yl)-2,2-dimethylpropanamide;SCHEMBL1643182;DTXSID40550791

Suppliers and Price of n-(4-Benzoylpyridin-3-yl)-2,2-dimethylpropanamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of n-(4-Benzoylpyridin-3-yl)-2,2-dimethylpropanamide

Chemical Property:

XLogP3:3.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:282.136827821
Heavy Atom Count:21
Complexity:381

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)C(=O)NC1=C(C=CN=C1)C(=O)C2=CC=CC=C2

Technology Process of n-(4-Benzoylpyridin-3-yl)-2,2-dimethylpropanamide

There total 8 articles about n-(4-Benzoylpyridin-3-yl)-2,2-dimethylpropanamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 82791-70-6
2,2-Dimethyl-N-<4-(hydroxyphenylmethyl)-3-pyridinyl>propanamide

: 112175-38-9
N-(4-benzoylpyridin-3-yl)-2,2-dimethylpropionamide

Guidance literature:: With manganese(IV) oxide; In toluene; for 3h; Heating;
DOI:10.1002/jhet.5570260119

Reference yield:

: 70298-88-3
N-(pyridin-3-yl)pivalamide

: 112175-38-9
N-(4-benzoylpyridin-3-yl)-2,2-dimethylpropionamide

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) n-BuLi / 1.) hexane, THF, -78 deg C, 15 m, 0 deg C, 3 h, 2.) THF, 25 deg C

2: 83 percent / pyridinium dichromate / dimethylformamide / 2 h / 25 °C

With dipyridinium dichromate; n-butyllithium; In N,N-dimethyl-formamide;
DOI:10.1139/v87-193

Reference yield:

: 100-52-7
benzaldehyde

: 112175-38-9
N-(4-benzoylpyridin-3-yl)-2,2-dimethylpropionamide

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) n-BuLi / 1.) hexane, THF, -78 deg C, 15 m, 0 deg C, 3 h, 2.) THF, 25 deg C

2: 83 percent / pyridinium dichromate / dimethylformamide / 2 h / 25 °C

With dipyridinium dichromate; n-butyllithium; In N,N-dimethyl-formamide;
DOI:10.1139/v87-193