COELENTERAZINE H

Base Information

Chemical Name:COELENTERAZINE H
CAS No.:50909-86-9
Molecular Formula:C26H21N3O2
Molecular Weight:407.472
Hs Code.:2933990090
Mol file:50909-86-9.mol

Synonyms:2-Deoxycoelenterazine;Coelenterazine h;Luciferin (Renilla);Renilla luciferin;h-Coelenterazine;

Suppliers and Price of COELENTERAZINE H

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Coelenterazine h
1mg
$ 285.00

Sigma-Aldrich
Coelenterazine h solid
50 μg
$ 164.00

Sigma-Aldrich
Coelenterazine h solid
50ug
$ 158.00

Matrix Scientific
2,8-Dibenzyl-6-(4-hydroxyphenyl)-imidazo[1,2-a]pyrazin-3(7H)-one 95%
5g
$ 2043.00

Matrix Scientific
2,8-Dibenzyl-6-(4-hydroxyphenyl)-imidazo[1,2-a]pyrazin-3(7H)-one 95%
1g
$ 681.00

Cayman Chemical
Coelenterazine h ≥95%
1mg
$ 307.00

Cayman Chemical
Coelenterazine h ≥95%
500μg
$ 162.00

American Custom Chemicals Corporation
COELENTERAZINE H 95.00%
5MG
$ 496.66

AK Scientific
Coelenterazine h
5g
$ 2808.00

AK Scientific
Coelenterazine h
1g
$ 969.00

Total 18 raw suppliers

Chemical Property of COELENTERAZINE H

Chemical Property:

Appearance/Colour:Yellow to brownish powder
Vapor Pressure:1.11E-14mmHg at 25°C
Melting Point:>200℃
Refractive Index:1.675
Boiling Point:593.5 °C at 760 mmHg
PKA:10.50±0.30(Predicted)
Flash Point:312.7 °C
PSA：70.39000
Density:1.26 g/cm³
LogP:4.57680
Storage Temp.:−20°C
Solubility.:Soluble in methanol, ethanol

Purity/Quality:

99%, ^*data from raw suppliers

Coelenterazine h ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Statements: 36/37/38
Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Description Coelenterazine-h (50909-86-9) may be used as a substrate in gene reporter assays, live cell assays, and biochemical assays (ELISA, BRET etc). Renilla luciferase catalyzes coelenterazine oxidation by oxygen to produce light. Coelenterazine-h produces 10-fold higher light output than native coelenterazine. Coelenterazine-h also undergoes autoluminescence, which is enhanced by superoxide anion and peroxynitrite in cells.
Uses Coelenterazine h, is a derivative of Coelenterazine (C636000), and iis more sensitive to Ca2+ than is the native complex, thus providing a valuable tool for measuring small changes in Ca2+ concentrations.

Technology Process of COELENTERAZINE H

There total 19 articles about COELENTERAZINE H which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 28.0%

: 19256-31-6
1,1-diethoxy-3-phenylpropane-2-one

: 40040-81-1
2-amino-3-benzyl-5-(4-methoxyphenyl)-pyrazine

: 50909-86-9
2,8-dibenzyl-6-(4-hydroxyphenyl)imidazo[1,20-a]pyrazin-3(7H)one

Guidance literature:: With hydrogenchloride; In ethanol; water; Reflux;

Reference yield:

: C₂₆H₁₉N₃O₂

: 50909-86-9
2,8-dibenzyl-6-(4-hydroxyphenyl)imidazo[1,20-a]pyrazin-3(7H)one

Guidance literature:: With ethylenediaminetetraacetic acid; β-nicotinamide adenine dinucleotide, disodium salt, reduced form; In water; dimethyl sulfoxide; at 25 ℃; for 0.166667h; pH=7.6; Reagent/catalyst; Enzymatic reaction;
DOI:10.1016/j.bbrc.2021.11.089