1H-Imidazole-2,5-dione,4-[[1,4-bis[(4-hydroxyphenyl)methyl]-1H-imidazol-2-yl]amino]-1-methyl-

Base Information

Chemical Name:1H-Imidazole-2,5-dione,4-[[1,4-bis[(4-hydroxyphenyl)methyl]-1H-imidazol-2-yl]amino]-1-methyl-
CAS No.:110189-04-3
Molecular Formula:C21H19 N5 O4
Molecular Weight:405.413
Hs Code.:
Mol file:110189-04-3.mol

Synonyms:IsonaamidineA

Suppliers and Price of 1H-Imidazole-2,5-dione,4-[[1,4-bis[(4-hydroxyphenyl)methyl]-1H-imidazol-2-yl]amino]-1-methyl-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 2 raw suppliers

Chemical Property of 1H-Imidazole-2,5-dione,4-[[1,4-bis[(4-hydroxyphenyl)methyl]-1H-imidazol-2-yl]amino]-1-methyl-

Chemical Property:

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 1H-Imidazole-2,5-dione,4-[[1,4-bis[(4-hydroxyphenyl)methyl]-1H-imidazol-2-yl]amino]-1-methyl-

There total 12 articles about 1H-Imidazole-2,5-dione,4-[[1,4-bis[(4-hydroxyphenyl)methyl]-1H-imidazol-2-yl]amino]-1-methyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 110189-02-1
4-[2-amino-1-(4-hydroxybenzyl)-1H-imidazol-4-ylmethyl]phenol

: 546113-06-8
1-methyl-3-trimethylsilylparabanic acid

: 110189-04-3
isonaamidine-A

Guidance literature:: 4-[2-amino-1-(4-hydroxybenzyl)-1H-imidazol-4-ylmethyl]phenol; 1-methyl-3-trimethylsilylparabanic acid; In chloroform; at 80 ℃; for 5h;

With cesium fluoride; In tetrahydrofuran; at 20 ℃; for 10h;

Reference yield:

: 2746-25-0
p-Methoxybenzyl bromide

: 110189-04-3
isonaamidine-A

Guidance literature:: Multi-step reaction with 7 steps

1.1: 96 percent / ethyl acetate / 2 h / 20 °C

2.1: 790 mg / aq. HCl / 2 h / 80 °C

3.1: 78 percent / NBS / tetrahydrofuran / 1 h / 0 °C

4.1: tert-BuLi / pentane; tetrahydrofuran / 0.25 h / -78 °C

4.2: 62 percent / trisyl azide / tetrahydrofuran; pentane / 1 h / -78 °C

5.1: 100 percent / hydrogen / 10 percent Pd/C / ethanol / 4 h / 20 °C

6.1: 100 percent / BBr₃ / CH₂Cl₂ / 1 h / 55 °C

7.1: CHCl₃ / 5 h / 80 °C

7.2: 80 percent / CsF / tetrahydrofuran / 10 h / 20 °C

With hydrogenchloride; N-Bromosuccinimide; hydrogen; tert.-butyl lithium; boron tribromide; palladium on activated charcoal; In tetrahydrofuran; ethanol; dichloromethane; chloroform; ethyl acetate; pentane;

Reference yield:

: 123-11-5
4-methoxy-benzaldehyde

: 110189-04-3
isonaamidine-A

Guidance literature:: Multi-step reaction with 10 steps

1.1: n-BuLi / tetrahydrofuran; hexane / 0.5 h / -78 °C

1.2: 87 percent / tetrahydrofuran; hexane / 1 h / -78 °C

2.1: 100 percent / triethylsilane; TFA / CH₂Cl₂ / 12 h / 20 °C

3.1: 95 percent / sodium borohydride; nickel(II) chloride hexahydrate / methanol; tetrahydrofuran / 12 h / 20 °C

4.1: 96 percent / ethyl acetate / 2 h / 20 °C

5.1: 790 mg / aq. HCl / 2 h / 80 °C

6.1: 78 percent / NBS / tetrahydrofuran / 1 h / 0 °C

7.1: tert-BuLi / pentane; tetrahydrofuran / 0.25 h / -78 °C

7.2: 62 percent / trisyl azide / tetrahydrofuran; pentane / 1 h / -78 °C

8.1: 100 percent / hydrogen / 10 percent Pd/C / ethanol / 4 h / 20 °C

9.1: 100 percent / BBr₃ / CH₂Cl₂ / 1 h / 55 °C

10.1: CHCl₃ / 5 h / 80 °C

10.2: 80 percent / CsF / tetrahydrofuran / 10 h / 20 °C

With hydrogenchloride; triethylsilane; sodium tetrahydroborate; N-Bromosuccinimide; n-butyllithium; hydrogen; tert.-butyl lithium; boron tribromide; trifluoroacetic acid; nickel dichloride; palladium on activated charcoal; In tetrahydrofuran; methanol; ethanol; hexane; dichloromethane; chloroform; ethyl acetate; pentane;