3-Propan-2-ylidene-2-benzofuran-1-one

Base Information

Chemical Name:3-Propan-2-ylidene-2-benzofuran-1-one
CAS No.:4767-54-8
Molecular Formula:C11H10O2
Molecular Weight:174.199
Hs Code.:
NSC Number:37419
DSSTox Substance ID:DTXSID60284480
Nikkaji Number:J615.523E
Wikidata:Q82019443
Mol file:4767-54-8.mol

Synonyms:4767-54-8;3-Isopropylidenephthalide;3-(Propan-2-ylidene)isobenzofuran-1(3H)-one;3-propan-2-ylidene-2-benzofuran-1-one;NSC37419;DTXSID60284480;UYTQKTLMMLDERF-UHFFFAOYSA-N;NSC-37419;3-(1-Methylethylidene)-2-benzofuran-1(3H)-one #

Suppliers and Price of 3-Propan-2-ylidene-2-benzofuran-1-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 9 raw suppliers

Chemical Property of 3-Propan-2-ylidene-2-benzofuran-1-one

Chemical Property:

Vapor Pressure:0.00189mmHg at 25°C
Boiling Point:292°C at 760 mmHg
Flash Point:118.2°C
Density:1.177g/cm³
XLogP3:2.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:174.068079557
Heavy Atom Count:13
Complexity:261

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(=C1C2=CC=CC=C2C(=O)O1)C

Technology Process of 3-Propan-2-ylidene-2-benzofuran-1-one

There total 2 articles about 3-Propan-2-ylidene-2-benzofuran-1-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 3043-64-9
1-phenyl-5-(propane-2-sulfonyl)-pr1H-tetrazole

: 85-44-9
phthalic anhydride

: 4767-54-8
3-(propan-2-ylidene)isobenzofuran-1(3H)-one

Guidance literature:: 1-phenyl-5-(propane-2-sulfonyl)-pr1H-tetrazole; phthalic anhydride; With boron trifluoride diethyl etherate; lithium hexamethyldisilazane; In tetrahydrofuran; at -78 ℃; for 0.75h; Inert atmosphere;

With acetic acid; In tetrahydrofuran; at -78 - 20 ℃; Inert atmosphere;

With silica gel; In tetrahydrofuran; Inert atmosphere;
DOI:10.1021/acs.orglett.6b02160

Reference yield:

: 61260-15-9
dimethyl (3-oxo-1,3-dihydroisobenzofuran-1-yl)phosphonate

: 67-64-1
acetone

: 4767-54-8
3-(propan-2-ylidene)isobenzofuran-1(3H)-one

Guidance literature:: With lithium hexamethyldisilazane; Yield given. Multistep reaction; 1.) THF, -78 deg C,1 h, 2.) THF, hexane, -78 deg C, 1 h then 12 h, RT;
DOI:10.1055/s-1994-25642