1(RS)-N-[4-[N-(4-Chlorophenylsulfonyl)carbamoyl]benzoyl]-L-valyl-N-[2-methyl-1-(trifluoroacetyl)propyl]-L-prolinamide

Base Information

Chemical Name:1(RS)-N-[4-[N-(4-Chlorophenylsulfonyl)carbamoyl]benzoyl]-L-valyl-N-[2-methyl-1-(trifluoroacetyl)propyl]-L-prolinamide
CAS No.:105080-50-0
Molecular Formula:C30H34 Cl F3 N4 O7 S
Molecular Weight:687.137
Hs Code.:
Mol file:105080-50-0.mol

Synonyms:ICI 200880

Suppliers and Price of 1(RS)-N-[4-[N-(4-Chlorophenylsulfonyl)carbamoyl]benzoyl]-L-valyl-N-[2-methyl-1-(trifluoroacetyl)propyl]-L-prolinamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 1(RS)-N-[4-[N-(4-Chlorophenylsulfonyl)carbamoyl]benzoyl]-L-valyl-N-[2-methyl-1-(trifluoroacetyl)propyl]-L-prolinamide

Chemical Property:

Density:1.358g/cm³

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 1(RS)-N-[4-[N-(4-Chlorophenylsulfonyl)carbamoyl]benzoyl]-L-valyl-N-[2-methyl-1-(trifluoroacetyl)propyl]-L-prolinamide

There total 2 articles about 1(RS)-N-[4-[N-(4-Chlorophenylsulfonyl)carbamoyl]benzoyl]-L-valyl-N-[2-methyl-1-(trifluoroacetyl)propyl]-L-prolinamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 79-37-8
oxalyl dichloride

: N-L-valyl-N-[3,3,3-trifluro-1-(1-methylethyl)-2-oxopropyl]-L-prolinamide, Hydrochloride Salt

: 7732-18-5
water

: 105080-63-5
4-[(4-Chlorophenyl)sulfonylaminocarbonyl] benzene carboxylic acid

: 105080-50-0
4-(4-chlorophenyl sulfonylcarbamoyl)benzoyl-L-valyl-L-prolyl-1-(RS)-(1-trifluoroacetyl-2-methylprolyl)amide

Guidance literature:: With NMM; In dichloromethane; N,N-dimethyl-formamide;

Reference yield:

: 4-(4-Chloro-benzenesulfonylaminocarbonyl)-benzoyl chloride

: N-L-valyl-N-<3,3,3-trifluoro-1-(1-methylethyl)-2-oxopropyl>-L-prolinamide hydrochloride

: 105080-50-0
4-(4-chlorophenyl sulfonylcarbamoyl)benzoyl-L-valyl-L-prolyl-1-(RS)-(1-trifluoroacetyl-2-methylprolyl)amide

Guidance literature:: With 4-methyl-morpholine; In dichloromethane; N,N-dimethyl-formamide; for 2.5h; Yield given; Ambient temperature;
DOI:10.1021/jm00052a013