(2R)-2-acetamido-3-[2-(4-chlorophenoxy)-2-methyl-propanoyl]sulfanyl-pr opanoic acid

Base Information

• Chemical Name: (2R)-2-acetamido-3-[2-(4-chlorophenoxy)-2-methyl-propanoyl]sulfanyl-pr opanoic acid
• CAS No.: 84489-15-6
• Molecular Formula: C₁₅H₁₈ClNO₅S
• Molecular Weight: 359.831
• Mol file: 84489-15-6.mol

Synonyms:Clofibrate mercapturate;

Chemical Property of (2R)-2-acetamido-3-[2-(4-chlorophenoxy)-2-methyl-propanoyl]sulfanyl-pr opanoic acid

Chemical Property:

• Vapor Pressure: 2.72E-14mmHg at 25°C
• Boiling Point: 580°Cat760mmHg
• Flash Point: 304.5°C
• PSA: 121.49000
• Density: 1.335g/cm³
• LogP: 3.18680

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (2R)-2-acetamido-3-[2-(4-chlorophenoxy)-2-methyl-propanoyl]sulfanyl-pr opanoic acid

There total 1 articles about (2R)-2-acetamido-3-[2-(4-chlorophenoxy)-2-methyl-propanoyl]sulfanyl-pr opanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

N-acetylcystein (616-91-1,7696-05-1) + clofibryl-S-acyl-glutathione → Clofibric acid (882-09-7) + clofibryl-S-acyl-N-acetylcysteine (84489-15-6)

Guidance literature:

With buffer; at 37 ℃; pH=7.4;

DOI:10.1021/tx010039x

upstream raw materials:

N-acetylcystein