17566-84-6

Usage

Uses

Used in Organic Synthesis:
(4-methylphenyl)phosphonic dichloride is used as a reagent for the introduction of phosphonate groups into various molecules, due to its reactivity typical of an acyl chloride.
Used in Pharmaceutical Industry:
(4-methylphenyl)phosphonic dichloride is used as a precursor in the synthesis of phosphonate esters, which have applications in the development of pharmaceuticals.
Used in Agrochemical Industry:
(4-methylphenyl)phosphonic dichloride is used as a precursor in the synthesis of phosphonate esters, which can be utilized in the development of agrochemicals.
Used in Materials Science:
(4-methylphenyl)phosphonic dichloride is used as a precursor in the synthesis of phosphonate esters, which can be applied in the field of materials science for the development of new materials.
Safety Precautions:
It is important to handle (4-methylphenyl)phosphonic dichloride with caution, as it can be corrosive and may release toxic fumes when exposed to water or moisture.

Upstream product

• 51303-75-4 tetrachloro-p-tolylphosphorane 
• 1754-46-7 diethyl 4-methylphenylphosphonate 
• 106-38-7 para-bromotoluene 
• 108-88-3 toluene 
• 537-64-4 bis(p-tolyl)mercury 
• 1005-32-9 p-tolyldichlorophosphine 

Downstream Products

• 142055-58-1 bis(4-methylphenyl) (4-methylphenyl)phosphonate 
• 60265-13-6 diphenyl 4-tolylphosphonate 
• 54948-52-6 1,2,5-tri-p-tolyl-1H-phosphole 
• 20443-15-6 p-tolyl-phosphonic acid diisocyanate 
• 51303-75-4 tetrachloro-p-tolylphosphorane 
• 58068-35-2 4-chloromethylphenylphosphonic dichloride 
• 66365-87-5 1,2,5-tri-p-tolyl-1H-phosphole 1-oxide 
• 1005-32-9 p-tolyldichlorophosphine 
• 3366-72-1 (4-methylphenyl)phosphonic acid 
• 18799-59-2 p-tolyl-phosphonic acid diamide 
• 701-32-6 p-tolyl-phosphonic acid-difluoride 

Relevant academic research and scientific papers

Reactions of aryltetrachlorophosphoranes with sodium dithionite and sulfuryl chloride

Reaction of aryltetrachlorophosphoranes with sodium dithionite or sulfuryl chloride leads to dichloroanhydrides of arylphosphonic acids in high yields. 1996 MAEe cyrillic signK Hayκa/Interperiodica Publishing.

Phosphorus-Containing Small Rings. IX. Reactions of Phosphorylated Methyl β-Chlorolactate Derivatives and Dialkyl 4-Chloromethylphosphonates with Salts of 2,2-Dimethyl-3-(2,2-dichlorovinyl)cyclopropanecarboxylic Acid

Methyl β-chlorolactate reacts with tri- and tetracoordinate phosphorus chlorides in the presence of an organic base to form l-methoxycarbonyl-2-chloroethyl esters of phosphorus acids. An improved method for obtaining 4-chloromethylphenylphosphonic acids w

N-hydroxylamines: Influence of Substituents on the Competitive Migration of Aryl and Phenyl Groups in the Lossen-like Rearrangement of their O-Methanesulphonyl Derivatives

The N-hydroxylamines ArPhP(O)NHOH (4) (Ar=p-XC6H4; X=MeO, Me, Cl, NO2) have been prepared from the corresponding phosphinic chlorides (3) using O-(trimethylsilyl)hydroxylamine and converted into the O-methanesulphonyl derivatives

Effect of para Substituents on Decomposition Rates of 2-(N,N'-Dimethylamino)ethyl Phenyl Phenylphosphonates

Spontaneous decomposition of nineteen of the title phosphonates to their 1,1,4,4-tetramethylpiperazinium salts was followed in 50 percent aqueous ethanol at different temperatures.The effect of substituents of the phenyl group on reaction rates was about

SYNTHESIS OF PHOSPHONIC DICHLORIDES AND CORRELATION OF THEIR P-31 CHEMICAL SHIFTS

Various mono-substituted diethyl arylphosphonates were prepared in good yield by treatment of aryl bromides or iodides with triethyl phosphite in the presence of NiCl2 or alternatively, addition of the aryl grignard reagent to diethyl phosphorochloridate.