ethyl 2,2-diphenylpropanoate

Base Information

• Chemical Name: ethyl 2,2-diphenylpropanoate
• CAS No.: 6337-61-7
• Molecular Formula: C17H18O2
• Molecular Weight: 254.329
• NSC Number: 37515
• DSSTox Substance ID: DTXSID10284516
• Wikidata: Q82019498
• Mol file: 6337-61-7.mol

Synonyms:6337-61-7;ethyl 2,2-diphenylpropanoate;NSC37515;DTXSID10284516;NSC-37515

Chemical Property of ethyl 2,2-diphenylpropanoate

Chemical Property:

• Vapor Pressure: 4.42E-05mmHg at 25°C
• Boiling Point: 350.3°Cat760mmHg
• Flash Point: 129.8°C
• Density: 1.063g/cm³
• XLogP3: 3.4
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 5
• Exact Mass: 254.130679813
• Heavy Atom Count: 19
• Complexity: 268

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCOC(=O)C(C)(C1=CC=CC=C1)C2=CC=CC=C2

Technology Process of ethyl 2,2-diphenylpropanoate

There total 3 articles about ethyl 2,2-diphenylpropanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

ethyl diphenylacetate (3468-99-3) + dimethyl sulfate (77-78-1) → 2,2-diphenyl-propionic acid ethyl ester (6337-61-7)

Guidance literature:

Multistep reaction; (i) NaH, (ii) /BRN= 635994/;

DOI:10.1021/jo01062a002

Reference yield:

2,2-diphenylpropionyl chloride (40997-78-2) → 2,2-diphenyl-propionic acid ethyl ester (6337-61-7)

Guidance literature:

DOI:10.1002/hlca.19550380108

Reference yield:

→ 2,2-diphenyl-propionic acid ethyl ester (6337-61-7)

Guidance literature:

Dianion (2) (Ph2C^--N^--N=CPh2)*2Na⁺, THF, Ethylchlorformat, CH3I, (-65grad);

DOI:10.1139/v70-314

upstream raw materials:

2,2-diphenylpropionyl chloride

ethyl diphenylacetate

dimethyl sulfate

Downstream raw materials:

2-methyl-3,3-diphenyl-butan-2-ol

2,2-diphenylpropan-1-ol

chloro-acetic acid-(2,2-diphenyl-propyl ester)

N,N-dimethyl-glycine-(2,2-diphenyl-propyl ester)