N',N',2-trimethylbenzohydrazide

Base Information

Chemical Name:N',N',2-trimethylbenzohydrazide
CAS No.:1130-97-8
Molecular Formula:C10H14N2O
Molecular Weight:178.234
Hs Code.:
DSSTox Substance ID:DTXSID001250105
Nikkaji Number:J1.312.581C

Synonyms:N',N',2-trimethylbenzohydrazide;SCHEMBL2451271;DTXSID001250105;1130-97-8;Benzoic acid, 2-methyl-, 2,2-dimethylhydrazide

Suppliers and Price of N',N',2-trimethylbenzohydrazide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of N',N',2-trimethylbenzohydrazide

Chemical Property:

XLogP3:1.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:178.110613074
Heavy Atom Count:13
Complexity:180

Purity/Quality:: 95% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC=CC=C1C(=O)NN(C)C

Technology Process of N',N',2-trimethylbenzohydrazide

There total 5 articles about N',N',2-trimethylbenzohydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 1128-86-5
1-benzoyl-2,2-dimethylhydrazine

: 74-88-4
methyl iodide

: 1130-97-8
2-methylbenzoic acid, 2,2-dimethylhydrazide

Guidance literature:: With N,N,N,N,-tetramethylethylenediamine; sec.-butyllithium; In tetrahydrofuran; at -78 ℃;
DOI:10.1016/S0040-4039(00)00462-7

Reference yield: 63.0%

: 118-90-1
ortho-methylbenzoic acid

: 57-14-7
N,N-Dimethylhydrazine

: 1130-97-8
2-methylbenzoic acid, 2,2-dimethylhydrazide

Guidance literature:: ortho-methylbenzoic acid; With oxalyl dichloride; N,N-dimethyl-formamide; In 1,2-dichloro-ethane; at 20 ℃; for 2h;

N,N-Dimethylhydrazine; With 4-methyl-morpholine; In 1,2-dichloro-ethane; at 20 ℃; for 20h; Cooling with ice;

Reference yield:

: 118-90-1
ortho-methylbenzoic acid

: 1130-97-8
2-methylbenzoic acid, 2,2-dimethylhydrazide

Guidance literature:: Multi-step reaction with 2 steps

1: oxalyl dichloride; N,N-dimethyl-formamide / dichloromethane / 3.17 h / 0 - 20 °C / Inert atmosphere

2: dichloromethane / 3.75 h / 0 - 20 °C / Inert atmosphere

With oxalyl dichloride; N,N-dimethyl-formamide; In dichloromethane;
DOI:10.1021/jacs.1c03780