Propanoic acid, 3-[2,3-dichloro-4-(1-oxobutyl)phenoxy]-

Base Information

• Chemical Name: Propanoic acid, 3-[2,3-dichloro-4-(1-oxobutyl)phenoxy]-
• CAS No.: 113239-48-8
• Molecular Formula: C13H14Cl2O4
• Molecular Weight: 305.158
• Mol file: 113239-48-8.mol

Synonyms:

Chemical Property of Propanoic acid, 3-[2,3-dichloro-4-(1-oxobutyl)phenoxy]-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Propanoic acid, 3-[2,3-dichloro-4-(1-oxobutyl)phenoxy]-

There total 1 articles about Propanoic acid, 3-[2,3-dichloro-4-(1-oxobutyl)phenoxy]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 14.0%

2,3-dichloro-4-(3-butenyloxy)butyrophenone (113239-47-7) → 3-(2,3-dichloro-4-butyrylphenoxy)propionic acid (113239-48-8)

Guidance literature:

With potassium permanganate; N-benzyl-N,N,N-triethylammonium chloride; In dichloromethane; water; at 20 ℃; for 1.5h;

DOI:10.1021/jm00131a008

Reference yield:

N,N-dimethylammonium chloride (506-59-2) + 3-(2,3-dichloro-4-butyrylphenoxy)propionic acid (113239-48-8) → 3-<2,3-dichloro-4-(2-methylenebutyryl)phenoxy>propionic acid (113239-16-0)

Guidance literature:

With acetic acid; paraformaldehyde; In N,N-dimethyl-formamide;

Reference yield:

3-(2,3-dichloro-4-butyrylphenoxy)propionic acid (113239-48-8) → 3-<2,3-dichloro-4-(2-methylenebutyryl)phenoxy>propionic acid (113239-16-0)

Guidance literature:

With N,N-dimethylammonium chloride; Yield given. Multistep reaction; 1.) AcOH, steam bath, 7 h, 2.) DMF, 60 deg C, 1 h;

DOI:10.1021/jm00131a008

upstream raw materials:

2,3-dichloro-4-(3-butenyloxy)butyrophenone

Downstream raw materials:

3-<2,3-dichloro-4-(2-methylenebutyryl)phenoxy>propionic acid

Refernces

• 1、 -. "Compounds useful in treating sickle cell anemia". . . Retrieved 2008/06/13.