2H-1,4-Benzoxazin-3(4H)-one, 2,4-dimethyl-7-(4-morpholinylmethyl)-1-oxo-2-propenyl)-, monohydrochloride

Base Information

Chemical Name:2H-1,4-Benzoxazin-3(4H)-one, 2,4-dimethyl-7-(4-morpholinylmethyl)-1-oxo-2-propenyl)-, monohydrochloride
CAS No.:136629-00-0
Molecular Formula:C18H23ClN2O4
Molecular Weight:366.8392
Hs Code.:
DSSTox Substance ID:DTXSID70929496

Synonyms:136629-00-0;2H-1,4-Benzoxazin-3(4H)-one, 2,4-dimethyl-7-(4-morpholinylmethyl)-1-oxo-2-propenyl)-, monohydrochloride;DTXSID70929496;LS-41974;2,4-Dimethyl-7-{2-[(morpholin-4-yl)methyl]prop-2-enoyl}-2H-1,4-benzoxazin-3(4H)-one--hydrogen chloride (1/1)

Suppliers and Price of 2H-1,4-Benzoxazin-3(4H)-one, 2,4-dimethyl-7-(4-morpholinylmethyl)-1-oxo-2-propenyl)-, monohydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2H-1,4-Benzoxazin-3(4H)-one, 2,4-dimethyl-7-(4-morpholinylmethyl)-1-oxo-2-propenyl)-, monohydrochloride

Chemical Property:

Vapor Pressure:4.01E-13mmHg at 25°C
Boiling Point:572.7°Cat760mmHg
Flash Point:300.1°C
Density:g/cm³
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:4
Exact Mass:366.1346349
Heavy Atom Count:25
Complexity:515

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1C(=O)N(C2=C(O1)C=C(C=C2)C(=O)C(=C)CN3CCOCC3)C.Cl

Technology Process of 2H-1,4-Benzoxazin-3(4H)-one, 2,4-dimethyl-7-(4-morpholinylmethyl)-1-oxo-2-propenyl)-, monohydrochloride

There total 4 articles about 2H-1,4-Benzoxazin-3(4H)-one, 2,4-dimethyl-7-(4-morpholinylmethyl)-1-oxo-2-propenyl)-, monohydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 58.0%

: 110-88-3
1,3,5-Trioxan

: 10024-89-2
morpholin hydrochloride

: 116337-69-0,123172-55-4
7-Acetyl-2,4-dimethyl-4H-benzo[1,4]oxazin-3-one

: 136629-00-0
7-(4-morpholino-2-methylenepropionyl)-2,4 dimethyl-2,3-dihydrobenzoxazin-<1,4>-3-one hydrochloride

Guidance literature:: In acetic acid; for 4h; Heating;

Reference yield:

: 54903-61-6
6-acetyl-3-methylbenzoxazolinone

: 136629-00-0
7-(4-morpholino-2-methylenepropionyl)-2,4 dimethyl-2,3-dihydrobenzoxazin-<1,4>-3-one hydrochloride

Guidance literature:: Multi-step reaction with 3 steps

1: 70 percent / aq. sodium hydroxide / Heating

2: 80 percent / sodium hydrogencarbonate / butan-2-one; H₂O / 8 h / 90 °C

3: 58 percent / acetic acid / 4 h / Heating

With sodium hydroxide; sodium hydrogencarbonate; In water; acetic acid; butanone;

Reference yield:

: 21892-80-8
3-methylbenzo[d]oxazol-2(3H)-one

: 136629-00-0
7-(4-morpholino-2-methylenepropionyl)-2,4 dimethyl-2,3-dihydrobenzoxazin-<1,4>-3-one hydrochloride

Guidance literature:: Multi-step reaction with 4 steps

1: 75 percent / polyphosphoric acid / 2 h / 75 °C

2: 70 percent / aq. sodium hydroxide / Heating

3: 80 percent / sodium hydrogencarbonate / butan-2-one; H₂O / 8 h / 90 °C

4: 58 percent / acetic acid / 4 h / Heating

With sodium hydroxide; PPA; sodium hydrogencarbonate; In water; acetic acid; butanone;